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Resources & Education Research Lab Listing Pennsylvania

Center for Genomic Sciences
Allegheny-Singer Research Institute
320 E North Avenue
Pittsburgh, Pennsylvania 15212 United States
Telephone: 412-359-6594
Hours: 8.30 am - 5.30 pm
Contact:  Mary 'O Toole

Hebda Wound Healing Research Lab
University of Pittsburgh School of Medicine
3550 Terrace Street
Pittsburgh, Pennsylvania 15261 United States
Telephone:
Hours:
Contact:  Pat Hebda: hebda@pitt.edu
Description: The Hebda lab is actively involved in research efforts to improve healing of the skin and mucosa of the head and neck.  Dr. Hebda is working with talented graduate students, residents and postdoctoral fellows and has a close collaboration with other faculty members, notably Joseph E. Dohar, M.D., a pediatric otolaryngologist and research partner.  The goal of their research team is to establish a multifaceted program encompassing preclinical and clinical projects.  The fundamental purpose is to develop new, biologically driven therapeutic modalities to promote and optimize wound healing and tissue regeneration of the skin and upper aerodigestive system.  To achieve this goal they have ongoing projects based on:
*    characterization of regenerative, or scarless, fetal wound healing
*    cell therapy and tissue engineering for laryngotracheal mucosa
*    animal and tissue culture model systems for airway injury
Another component of their research involves characterization of the fibrotic fibroblast phenotype as exhibited in connective tissue scars, such as keloids and hypertrophic scars in the skin and stenoses of the airway.  The group is pursuing this study of fibrotic healing with scar formation in children and adults in contrast to the scarless regenerative healing of fetal connective tissues of skin and airway mucosa.

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