2019 Winner

INJECTABLE CELLULAR PLACENTAL FORMULATION PREVENTS BLEOMYCIN INDUCED DERMAL FIBROSIS IN AGED MICE
Sandeep Dhall

---

2018 Winner

Amitava Das, PhD
The Ohio State University

Finalists: Sandeep Dhall, Yong Mao, Rusty L. Montgomery, Kristo Nuutila, Randolph Stone, Cornelia Weigand, Ping Xie

---

2017 Winner

P.IRD01 - RE-ENGINEERING A FIBRONECTIN-DERIVED PEPTIDE FOR TOPICAL TREATMENT OF BURNS AND CHRONIC WOUNDS
R. A. Clark, A. J. Singer, F. Lin
NeoMatrix Therapeutics, Inc., Stony Brook, NY, USA

---

2016 Winner

P.IRD04 - REGULATION OF ECM PRODUCTION AND FIBROSIS BY MRG-201, A MIMIC OF MICRORNA MIR-29
C. L. Gallant-Behm¹, J. Piper¹, K. Hutnick¹, X. Beatty¹, R. L. Montgomery¹, G. Yu², N. Kaminski², E. Van Rooij³, C. M. Dalby¹, A. L. Jackson^1
1MiRagen Therapeutics Inc, Boulder, CO, USA, ²Yale University School Of Medicine, New Haven, CT, USA, ³Hubrecht Institute, Utrecht, UTRECHT, Netherlands

---

2015 Winner

P.II04 - UNIQUE FEATURE OF LIVING AMNIOTIC TISSUE: CELL PROTECTION FROM OXIDANT-INDUCED DAMAGE VIA THE RELEASE OF ANTI-OXIDANT MEDIATORS
Y. Arnold, A. Gyurdieva, A. Johnson, A. Danilkovitch
Osiris Therapeutics, Columbia, MD USA

---

2014 Finalists

FIRST PLACE: BIO.12 - CONTROLLED RELEASE OF NITRIC OXIDE THROUGH ZEOLITE SACHETS
M. Neidrauer¹, A. Bhattacharyya², S. Julius², C. Moorehead², J. Belle³, K. A. Barbee², S. G. Joshi^3
1Zeomedix, Inc., Exton, PA USA, ²Drexel University, Philadelphia, PA USA, ³Drexel University College Of Medicine, Philadelphia, Pa USA

CW.01 - A POLYURETHANE FOAM WOUND DRESSING CONTAINING A BOUND CATIONIC POLYMER RAPIDLY KILLS PLANKTONIC BACTERIA AND PREVENTS BIOFILM FORMATION IN THE PRESENCE OF SERUM
B. Liesenfeld¹, P. L. Tran⁴, A. De Souza⁵, D. Mehta⁵, G. S. Schultz^1,2, A. Hamood³, T. W. Reid^3,4
1Quick-Med Technologies, Inc., Gainesville, FL USA, ²University Of Florida, Gainesville, FL USA, ³Texas Tech Unversity, Lubbock, TX USA, ⁴Texas Tech Unversity, Lubbock, TX USA, ⁵Viridis Biopharma Ltd., Mumbai, MAHARASHTRA India

CW.13 - AN IN VIVO EFFICACY EVALUATION OF VARIOUS WOUND TREATMENT PRODUCTS FOR THEIR RELATIVE DEBRIDEMENT ACTIVITY, USING A PORCINE WOUND ESCHAR MODEL
K. Lam¹, H. Somers², P. S. Attar^1
1BRIDGE PTS, Inc., San Antonio, TX USA, ²Hydrofera Blue, Libertyville, IL USA

---

2013 Finalists

FIRST PLACE: BRC.07 - MIR29: A NOVEL REGULATORY FUNCTION OF MIR 29 IN KELOID FORMATION
G. Zhang, MD, Z. Li, MD, W. Gao, MD, A. Wang, MD, D. Lin, MD, J. Yang, MD
Department Of Hand And Plastic Surgery, The 2nd Affiliated Hospital Of Wenzhou Medical College, Wenzhou, ZHEJIANG, China

BRC.01 - THE IMPORTANCE OF STEM CELLS IN A BILAYERED LIVING CELLULAR CONSTRUCT USED TO HEAL CHRONIC WOUNDS
M. W. Carlson, PhD, M. Jackman, D. Bakshb, PhD
Organogenesis, Inc., Canton, MA, USA

BRC.02 - ANTIMICROBIAL EFFICACY OF A TOPICAL OINTMENT CONTAINING NITRIC OXIDE LOADED ZEOLITE
M. Neidrauer, PhD¹, U. K. Ercan BS², A. Bhattacharyya, BS, MESc², R. Trikha, BS², K. A. Barbee, PhD², S. G. Joshi, MD, PhD, MS^3
1Zeomedix, Inc., Malvern, PA, ²Drexel University, Philadelphia, Pennsylvania, ³Drexel University College Of Medicine, Philadelphia, PA, USA

BRC.03 - THE IMPORTANCE OF TWO CELL TYPES IN A BILAYERED LIVING CELLULAR CONSTRUCT IN RESPONSE TO TNF-ALPHA STIMULUS
M. Fakharzadeh, A. Wojtowicz, PhD, B. Lamothe, BS, D. Baksh, PhD
Organogenesis, Inc., Canton, MA, USA

BRC.04 - A MODIFIED COLLAGEN GEL ENHANCES HEALING OUTCOME IN A PRE-CLINICAL SWINE MODEL OF EXCISIONAL WOUNDS
H. Elgharably, MD, S. Roy, PhD, S. Khanna, PhD, M. Abas, BS, P. D. Ghatak, A. Das, K. Mohammed, MD, C. K. Sen, PhD
The Ohio State University, Columbus, OH, USA

BRC.05 - IMPROVEMENT OF HUMAN KERATINOCYTE MIGRATION BY A REDOX ACTIVE BIOELECTRIC DRESSING
P. D. Ghatak, J. Banerjee, S. Khanna, PhD, S. Roy, PhD, C. K. Sen, PhD
Comprehensive Wound Center, Davis Heart & Lung Research Institute, Columbus, OHIO, USA

BRC.06 - THE EFFECT OF PULSED RADIO FREQUENCY ELECTROMAGNETIC (PRFE) FIELDS ON ORGANOTYPIC CULTURES OF NON DIABETC AND DIABETIC TISSUE USING RT-PCR AND MICROARRAY ANALYSIS
J. Moffett, PhD¹, R. G. Frykberg², J. J. Banks², D. Hardy, BS², L. M. Fray, BS, ^1
1Regenesis Biomedical, Scottsdale, Arizona, ²Carl T. Hayden VA Medical Center, Phoenix, Arizona

---

2012 Finalists

FIRST PLACE: BRC.02 - HUMAN RECOMBINANT TYPE-I COLLAGEN BASED SCAFFOLDS, INNOVATIVE EFFECTIVE BIOMATERIAL FOR CUTANEOUS WOUND HEALING
S. Shilo, PhD, MD¹, S. Roth¹, T. Amzel¹, T. Harel-Adar, PhD¹, F. Grynspan, PhD¹, O. Shoseyov, PhD^1,2
1CollPlant Ltd, Ness-Ziona, Israel, ²The Hebrew University Of Jerusalem, Rehovot, Israel

SECOND PLACE: BRC.04 - EVALUATION OF DOSING EFFECTS OF A HUMAN FIBROBLAST-DERIVED DERMAL SUBSTITUTE (DS) ON WOUND CLOSURE IN A FULL-THICKNESS DERMAL WOUND MODEL IN ATHYMIC RATS
C. S. Young, PhD, C. E. Wilkins-Port, PhD, C. Self, C. E. Hart, PhD
Advanced BioHealing, Brentwood, TN, USA

THIRD PLACE: BRC.05 - HEALING CHARACTERISTICS OF FULL-THICKNESS WOUNDS TREATED WITH A BILAYERED LIVING CELLULAR CONSTRUCT IN DIABETIC MINIATURE SWINE
J. Qiao, MD, PhD, E. Medeiros, BS, T. Bollenbach, PhD, D. Bates, MD, PhD
Organogenesis Inc., Canton, MA, USA

2012 Finalists and Runner Ups

BRC.03 - THE EFFECT OF PULSED RADIO FREQUENCY ELECTROMAGNETIC (PRFE) FIELDS ON OXIDATIVE STRESS PATHWAYS INVOLVED IN THE INFLAMMATORY PHASE OF WOUND HEALING
J. Moffett, PhD, L. M. Fray, BS
Regenesis Biomedical, Inc, Scottsdale, AZ USA

BRC.06 - EVALUATION OF WOUND DEBRIDEMENT EFFICACY OF PROTEOLYTIC ENZYMES FROM THE FUNGUS ASPERGILLUS MELLEUS
L. Shi, PhD, A. Jovanovic, PhD, S. Tetens, BS, C. Langat, E. Roche, PhD, D. Carson, PhD, DABT Healthpoint Biotherapeutics, Fort Worth, TX, USA

BRC.07 - CAUTION WHEN COMBINING WOUND PRODUCTS
G. Schultz, PhD^{1, 2}, B. Liesenfeld, PhD², A. Mikhaylova, PhD², J. Olderman, PhD², P. Phillips, PhD^1
1University Of Florida, Gainesville, Fl, USA, ²Quick-Med Technologies, Inc, Gainesville, Fl, USA

---

2011 Finalists

FIRST PLACE: BRC.04 - IMPROVED HEALING IN WEANLING PIG MODEL OF VESICANT INJURY SHOWN BY HIGH FEATURE ANTIMICROBIAL DRESSING

B. Liesenfeld, PhD¹, A. Mikhaylova, PhD¹, G. S. Schultz, PhD^{1, 2
1}Quick-Med Technologies, Gainesville, FL ²University Of Florida, Gainesville, FL

SECOND PLACE: BRC.14 - THROMBIN PEPTIDE TP508 STIMULATES DERMAL WOUND HEALING IN GAMMA-IRRADIATED ICR MICE B.

B. Olwzewska-Pazdrak, MD^{1, 4}, K. Burckart, BS¹, T. Toliver-Kinsky, PhD², B. Loucas, PhD³, M. Cornforth, PhD³, D. Carney, PhD^{1, 4
1}Department Of Biochemistry & Molecular Biology, University Of Texas Medical Branch, Galveston, TX, ²Dept Of Anesthesia, University Of Texas Medical Branch, Galveston, TX, ³Dept Of Radiation Oncology And Biolocy, Galveston, TX, ⁴RADIX Therapeutics, LLC, Galveston, TX

THIRD PLACE: BRC.02 - UNIQUE DRUG DRAMATICALLY AUGMENTS WOUND CLOSURE AND SCARRING BY ACCELERATING CRITICAL HEALING STAGES.
L. Braiman-Wiksman, PhD, E. Braude, MD, E. Brener, PhD, M. Ben-Hamo, BA, R. Mandil Levin, PhD, T. Tennenbaum, MD, PhD
Heal-Or Ltd., Rehovot, ISRAEL

2011 Finalists and Runner Ups

BRC.01 - WOUND HEALING CHARACTERISTICS OF TWO TYPES OF ACUTE FULL THICKNESS WOUNDS IN THE PRESENCE OF A LIVING CELLULAR CONSTRUCT IN A HANFORD MINIATURE SWINE MODEL
T. J. Bollenbach, PhD, E. Medeiros, BS, D. Bates, MD, PhD
Organogenesis Inc., Canton, MA

BRC.03 - THE EFFECTS OF A NOVEL SPRAYABLE SKIN EQUIVALENT ON WOUND HEALING
B. M. Kiedaisch¹, E. Rolland, PhD², D. Carson, PhD, DABT^1
1HealthPoint Ltd., Fort Worth, TX, ²DFB Bioscience, Lausanne, NA

BRC.05 - NATURAL POLYMERS FOR CRANIOFACIAL ENGINEERING
M. A. Lokuta, PhD, K. R. Gratz, PhD, B. M. Steiglitz, PhD, J. C. Pirnstill, BS, K. K. Schaeve, BS, T. F. Wiesner, BS, M. L. Bucholtz, BA, S. Sisson, BS, B. L. Allen-Hoffmann, PhD
Stratatech Corporation, Madison, WI

BRC.06 - DEFICIENT DERMAL REMODELING CORRECTED BY ADULT AND FETAL FIBROBLASTS TRANSPLANTATION
C. C. Yates, PhD^{1, 2}, D. L. Whaley, BS, MS², A. Wells, MD, DMSc^{1, 2
1}University Of Pittsburgh School Of Medicine Department Of Pathology, Pittsburgh, PA, ²Pittsburgh Veterans Affair Medical Center, PIttsburgh, PA

BRC.07 - THE PROLONGED INFLAMMATORY RESPONSE IN DIABETIC WOUND HEALING IS ASSOCIATED WITH DOWN-REGULATION OF MICRORNA 146A
J. Xu, PhD, W. Wu, BS, L. Zhang, W. Dorsett-Martin, M. E. Mitchell, MD, K. W. Liechty, MD
¹University Of Mississippi Medical Center, Jackson, MS

BRC.08 - EVALUATION OF ANTI-INFLAMMATORY EFFECT OF CLOSTRIDIUM COLLAGENASE AND ITS COLLAGEN DEGRADATION PRODUCTS
L. Shi, PhD, B. Kiedaisch, R. Ermis, BS, N. Hudson, D. Carson, PhD, DABT
Healthpoint, Ltd., Fort Worth, TX

BRC.09 - TISSUE-BASED CYTOKINE IMMUNOTHERAPY FOR SKIN CANCER
M. A. Lokuta, PhD, A. R. Comer, PhD, B. L. Soto, PhD, M. Vander Zanden, BS, M. L. Bucholtz, BS, B. L. Allen-Hoffmann, PhD
Stratatech Corporation, Madison, WI

BRC.10 - HUMAN BONE MARROW, ENDOTHELIAL AND MESENCHYMAL CELLS HAVE SIGNIFICANT EFFECTS IN REPAIRING HUMAN ISLET INJURY IN VITRO.
L. Luo, MD¹, F. Xiong¹, J. Z. Luo, BS^{1, 2
1}Stem Cell Biology, Roger Williams Hospital, Boston University, Shool Of Medicine, Providence, RI, ²Brown Alpart Medical School, Providence, RI

BRC.11 - USE OF A COLONY-FORMING EFFICIENCY (CFE) ASSAY TO SELECT ROBUST KERATINOCYTE CELL LINES FOR BILAYERED LIVING CELL CONSTRUCT (BLCC) GENERATION
Z. Guo, PhD, D. Baksh, PhD.
Organogenesis Inc., Canton, MA

BRC.12 - MODIFICATION OF NANOPARTICLE AGGREGATE SURFACES TO AFFECT BACTERIAL MIGRATION AND BIOFILM FORMATION
J. V. St. John, PhD
ULURU, Addison, TX

BRC.13 - SUBCUTANEOUS ADIPOCYTES IN WOUND HEALING - THE ROLE OF ADIPONECTIN.
R. Mandil Levin, PhD, M. Ben Hamo, BA, L. Braiman-Wiksman, PhD, T. Tennenbaum, MD, PhD
Heal-Or Ltd., Rehovot, Israel

---

2010 Winner

SUSTAINED EXPRESSION OF ANGIOGENIC FACTORS STIMULATES VASCULARIZED GRANULATION TISSUE DEPOSITION IN DIABETIC MICE
Allen Comer, PhD¹, Joely Straseski, PhD², Sara Pirnstill, BS¹, Kristi Schaeve, BS¹, Maggie Bach¹, Jennifer Murphy, MD², Lynn Allen-Hoffmann, PhD^1
1Stratatech Corporation, Madison, Wisconsin, ²University of Wisconsin-Madison, Madison, Wisconsin

---

2009 Winner

INHIBITION OF MULTIDRUG-RESISTANT ACINETOBACTER BAUMANNII BY NON-VIRAL EXPRESSION OF HCAP-18 IN A BIOENGINEERED HUMAN SKIN TISSUE
John Centanni, Christina Thomas-Virnig, PhD, Colette Johnston, Li-Ke He, MD, Sandy Schlosser, Kelly Van Winkle, Ruibing Chen, Angela Gibson, Andrea Szilagyi, Lingjun Li, PhD, Shankar Ravi, PhD, B. Lynn Allen-Hoffmann, PhD

---

2008 Winner

THE ELECTRIC FIELD AT HUMAN SKIN WOUNDS DECLINES SHARPLY WITH AGE
Richard Nuccitelli, Pamela Nuccitelli, Changyi Li, Suman Narsing, David Vendt, David Pariser, Antoinette Hood

---

2007 Winner

IN SITU PROTEOMICS OF WOUNDS USING FORMALLIN FIXED PARAFFIN EMBEDDED TISSUE
Patrick J. Parks

---

2006 Winner

A NOVEL MOIST WOUND HEALING DRESSING THAT PROVIDES SUSTAINED ANTIMICROBIAL ACTIVITY AND PROTEASE INHIBITION TO SPEED WOUND HEALING
Bernd Liesenfeld, Gregory Schultz, William Toreki, Roy Carr, David Moore, Christopher Batich, Gerald Olderman
Quick-Med Technologies, University of Florida

---

2005 Winner

THE BIOELECTRIC FIELD IMAGER: A NEW TOOL FOR MEASURING THE ELECTRONIC FIELD AROUND SKIN WOUNDS
Pamel Nuccitelli, President and Richard Nuccitelli, VP, R&D
RPN Research

---

2004 Winner

ALPHA1-ANTICHYMOTRYPSIN - A HUMAN SERPIN WITH THE POTENTIAL TO HEAL DIABETIC ULCERS
Andreas Goppelt
SWITCH Biotech AG, Germany