Wound Healing Society
2019 Annual Meeting Program

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DAY 1: TUESDAY, MAY 7, 2019
8:00 am - 8:15 am
WHS WELCOME AND INTRODUCTION
Sashwati Roy, PhD; Timothy W. King, MD, PhD; Praveen R. Arany, DDS, PhD
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8:15 am - 9:15 am
WHS SESSION A: Wound Healing Foundation Thomas K. Hunt Lecturer (non-accredited)
Moderators: Laura K.S. Parnell, BS, MS, CWS; Sashwati Roy, PhD
Speaker: George Brooks, MD
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9:15 am - 9:30 am
BREAK
9:30 am - 11:00 am
WHS SESSION B: Wound Healing in Military Medicine
Moderators: Robert Christy, MD; Lloyd Rose, MD
Speaker: Anders Carlsson, PhD; Kai Leung, MD; Elof Eriksson, MD, FACS
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11:00 am - 11:15 am
BREAK
11:15 am - 12:45 pm
WHS Session C: Growth Factors and Biomolecules
Moderators: Anie Philip, PhD
Speakers: Anie Philip, PhD; Marjana Tomic-Canic, PhD
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12:45 pm - 2:00 pm
SHARK TANK LUNCH
Moderators: Vickie Driver, DPM; Mitchell Sanders, PhD; Gary Robinson, PhD
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2:00 pm - 3:30 pm
WHS Session D: Advances in Wound Technologies
Moderators: Jeffrey M. Davidson, PhD; Traci A. Wilgus, PhD
Speaker: Praveen R. Arany, DDS, PhD; Sashwati Roy, PhD; Akhilesh Gaharwar, PhD
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3:30 pm - 3:45 pm
BREAK
3:45 pm - 5:15 pm
WHS Session E: Clinical Research Excellence in Diabetic Foot Ulcers
Moderators: Theresa Jones, Geoffrey C. Gurtner MD
Speaker: Gayle M. Gordillo, MD; Geoffrey C. Gurtner, MD; Michael S. Conte, MD, FACS; Peter Rubin, MD; James Wrobel, MD; Robert S. Kirsner, MD
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6:30 pm - 9:30 pm
SOCIAL EVENT FOR WHS MEMBERS
Briscoe Western Art Museum

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Registered WHS members are invited to attend. (Walking Directions Provided)
Supported By:
AliraHealth

DAY 2: WEDNESDAY, MAY 8, 2019
7:30 am - 9:00 am
WHS COMMITTEE MEETINGS
9:00 am - 9:15 am
BREAK
9:15 am - 9:30 am
SAWC SPRING OPENING CEREMONY
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9:30 am - 10:30 am
NEW SURGICAL CASE KEYNOTE ADDRESS
Speaker: Geoffrey Gurtner, MD, FACS; William Marston, MD
10:30 am - 10:45 am
BREAK
10:45 am - 11:45 am
WHS Session F: Regenerative Medicine and Stem Cells
Moderators: Chandan K. Sen, PhD; Luisa Ann DiPietro, DDS, PhD
Speaker: Chandan K. Sen, PhD; Michael Murphy, MD
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11:45 am - 12:00 pm
BREAK
12:00 pm - 1:30 pm
INDUSTRY-SUPPORTED LUNCH SYMPOSIA
1:30 pm - 1:45 pm
BREAK
1:45 pm - 4:00 pm
WHS Session G: YOUNG INVESTIGATORS SYMPOSIUM
Moderators: Sashwati Roy, PhD; Geoffrey C. Gurtner, MD; Phil Stevens, PhD
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1:45
G.01. Granzyme B Exacerbates Atopic Dermatitis Through Filaggrin, E-cadherin And Desmoglein Cleavage And Disruption Of Barrier Function
Christopher Turner1, Stephanie Santacruz1, Matthew Zeglinski1, Christine Wang1, Katlyn Richardson1, Sho Hiroyasu1, Hongyan Zhao1, Yue Shen1, Gail Gauvreau2, Hermenio Lima2, Roma Sehmi2, David Granville1
1University of British Columbia, Vancouver, BC, Canada, 2McMaster University, Hamilton, ON, Canada
2:00
G.02. EPIDERMAL STEM CELL DERIVED EXOSOMES IMPROVE DIABETIC WOUND HEALING BY MODULATING FIBROBLAST AND MACROPHAGE FUNCTIONS
Georgios Theocharidis, Peng Wang, Antonio Lobao, Biaoliang Wu, Aristidis Veves
Beth Israel Deaconess Medical Center, Boston, MA, USA
2:15
G.03. MECHANICAL TENSION INFLUENCES THE REGULATORY LANDSCAPE OF MSC-DERIVED EXOSOMES DURING WOUND HEALING
Hima Vangapandu1, Matthew Robertson1, Daniel Colchado1, Natalie Templeman1, Hui Li1, Yao Ning1, Alexander Blum1, Paul Bollyky2, Sundeep Keswani1, Cristian Coarfa1, Swathi Balaji1
1Baylor College of Medicine, Houston, TX, USA, 2Stanford University, Palo Alto, CA, USA
2:30
G.04. POSSIBILITY OF INJECTING ADIPOSE-DERIVED STROMAL VASCULAR FRACTION CELLS TO ACCELERATE MICROCIRCULATION IN ISCHEMIC DIABETIC FEET
Seung-Kyu Han, Ji Won Son, Jae youn Kim, Sik Namgoong
Korea University Guro Hospital, Seoul, Korea, Republic of
2:45
G.05. PYOCYANIN INDUCES MITOCHONDRIAL DYSFUNCTION IN THE BIOFILM INFECTED CUTANEOUS WOUND THROUGH UPREGULATION OF MIR-146A
Karamjeet Kaur, Mithun Sinha, Sashwati Roy, Chandan K. Sen
Indiana University, Indianapolis, IN, USA
3:00
G.06. HYPERSPECTRAL IMAGING IN BURN EVALUATION FROM BENCH TO BEDSIDE: A CASE REPORT
Garrick Gu, BA, Melissa J. McCarthy, MPH, Jorge Lujan-Hernandez, MD, Danielle Stamer, BS, Janice Lalikos, MD
University of Massachusetts Medical School, Worcester, MA, USA
3:15
G.07. TARGETING CD109 IN DUPUYTREN'S DISEASE
Yasser Almadani1, Ana Maria Pena Diaz2, Kenneth Finnson1, David O'Gorman2, Anie Philip1
1McGill University, Montreal, QC, Canada, 2Western University, London, ON, Canada
3:30
G.08. EPIGENETIC MAPPING OF WOUND EDGE FROM CHRONIC WOUND PATIENTS USING NEXT GENERATION SEQUENCING
Kanhaiya Singh1, Sashwati Roy1, Durba Pal2, Subhadip Ghatak1, Dolly Khona1, Saba Tabasum1, Shomita Steiner1, Devleena Das1, Pearlly Yan2, Ralf Bundschuh2, Savita Khanna1, Chandan K. Sen1
1Indiana University School of Medicine, Indianapolis, IN, USA, 2The Ohio State University, Columbus, OH, USA
3:45
G.09. ETRS WINNER
SYSTEMIC DELIVERY OF ANTI-INTEGRIN ANTIBODIES REDUCE EARLY MACROPHAGE RECRUITMENT, INFLAMMATION AND SCAR FORMATION IN MURINE BURN WOUNDS

Xanthe L. Strudwick1, Damian H. Adams1, Natasha T. Pyne2, Michael S. Samuel2, Rachael Z. Murray3, Allison J. Cowin1
1Future Industries Institute, University of South Australia, Adelaide, Australia, 2Centre for Cancer Biology, University of South Australia, Adelaide, Australia, 3Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
4:00 pm - 4:15 pm
BREAK
4:15 pm - 5:15 pm
WHS SESSION H: CONCURRENT ORAL ABSTRACTS (non-accredited)
Oral abstract presentations will feature the highest scoring abstracts submitted to the WHS.
 
H1: BIOENGINEERING/BIOMATERIALS
Moderators: Mitchell Sanders, PhD; John McQuilling, PhD
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4:15
H1.01. BIOMIMETIC ADIPIOSE STEM CELL DRESSING FOR SKIN REGENERATION
Artem Trotsyuk, Clark A. Bonham, Melanie Rodrigues, Paul Mittermiller, Jayakumar Rajadas, Mohammed Inayathullah, Geoffrey Gurtner
Stanford University, Stanford University, CA, USA
4:25
H1.02. LOW COST OXYGEN-SENSING FILMS FOR CLINICAL WOUND HEALING MONITORING
Daniel Naveed Tavakol, Samantha Schwager, Lindsay Jeffries, Anthony Bruce, Christopher DeRosa, Cassandra Fraser, Shayn M. Peirce, Patrick S. Cottler
University of Virginia, Charlottesville, VA, USA
4:35
H1.03. REAL-TIME TRACKING AND QUANTIFICATION OF CHRONIC WOUND BACTERIA VIA NANOFIBER BIOSENSORS
Craig Miller, Mark Livingstone, Jordon Gilmore
Clemson University, Clemson, SC, USA
4:45
H1.04. CUSTOMIZABLE ELECTROSPUN SCAFFOLDS FOR SUSTAINED AND LOCAL DELIVERY OF SIRNA IN DIABETIC FOOT ULCERS
Amy C. Kauffman1, Alexandra S. Piotrowski-Daspit1, Themis Kyriakides2, W. Mark Saltzman1
1Yale University, New Haven, CT, USA, 2Yale School of Medicine, New Haven, CT, USA
4:55
H1.05. DEHYDRATED AMNION CHORION MEMBRANES INDUCE BROAD-SCALE CHANGES IN KINASE ACTIVITY OF ENDOTHELIAL CELLS
Miranda Burnette, John McQuilling, MaryRose Kammer, Kelly Kimmerling, Katie Mowry
Organogenesis Inc, Birmingham, AL, USA
5:05
H1.06. MID-INFRARED LASER-ACTIVATED RAPID SOFT TISSUE REPAIR AND REGENERATION
Inam Ridha1, Deepanjan Ghosh1, Ali Basiri1, Jung Keun Lee2, Jacquelyn Kilbourne1, Yu Yao1, Kaushal Rege1
1Arizona State University, Tempe, AZ, USA, 2Midwestern University, Glendale, AZ, USA
 
H2: FIBROSIS/SCARRING I
Moderators: Heather Powell, PhD; Latha Satish, PhD
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4:15
H2.01. COLLAGEN-PRODUCING MACROPHAGES CONTRIBUTE TO FIBROSIS
Britta A. Kuehlmann, Clark A. Bonham, Geoffrey C. Gurtner
Stanford University, Stanford, CA, USA
4:25
H2.02. OPEN ABDOMENS WITH ONGOING INTRAABDOMINAL PATHOLOGIES SUCCESSFULLY CLOSED USING A DYNAMIC TISSUE SYSTEM AND BIOLOGIC XENOGRAFT: A CASE SERIES
Beatrice Caballero, Yana Puckett, Michelle Estrada, Shirley McReynolds, Robyn Richmond, Catherine Ronaghan
Texas Tech University Health Sciences, Lubbock, TX, USA
4:35
H2.03. TARGETING WNT SIGNALING TO REDUCE FIBROSIS
Britta A. Kuehlmann, Clark A. Bonham, Geoffrey C. Gurtner
Stanford University, Stanford, CA, USA
4:45
H2.04. EVIDENCE THAT FETUIN-A CONTRIBUTES TO CUTANEOUS SCAR FORMATION
Nicholas K. Pappa, Brian C. Wulff, Traci A. Wilgus
Ohio State University, Columbus, OH, USA
4:55
H2.05. FIBROSIS AROUND IMPLANTS IS DRIVEN BY THREE UNIQUE SUBGROUPS OF MACROPHAGES
Britta A. Kuehlmann, Clark A. Bonham, Geoffrey C. Gurtner
Stanford, Stanford, CA, USA
5:05
H2.06. MELANOCYTE RE-POPULATION AND CUTANEOUS RE-INNERVATION IN TEMPORAL WOUND HEALING AND SCAR FORMATION IN HUMAN SKIN
Sara Ud-Din1, Philip Foden2, Katie Stocking2, Douglas McGeorge3, Ardeshir Bayat1
1University of Manchester, Manchester, United Kingdom, 2Manchester University Foundation Trust, Manchester, United Kingdom, 3Nuffield Grosvenor Hospital, Chester, United Kingdom
 
H3: INFECTION/BIOFILM
Moderators: Swathi Balaji, PhD; Joshua Tam, PhD
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4:15
H3.01. COMPARISON OF PSEUDOMONAS AERUGINOSA BIOFILM INFECTION IN PARTIAL- AND FULL-THICKNESS BURN WOUNDS
Kenneth S. Brandenburg, Alan J. Weaver, Jr, Liwu Qian, Tao You, Ping Chen, SL Rajasekhar Karna, Shaina L. Van Stryk, Uzziel Pineda, Kai P. Leung
US Army Institute of Surgical Research, JBSA FT Sam Houston, TX, USA
4:25
H3.02. STAPHYLOCOCCUS EPIDERMIS AND STAPHYLOCOCCUS AUREUS DIFFERENTIALY MODULATE ANTIMICROBIAL MOLECULE PERFORIN-2 DURING WOUND HEALING
Vivien Chen, Irena Pastar, Cheyanne R. Head, Katelyn O’Neill, Jamie Burgess, Natasa Strbo, Marjana Tomic-Canic
University of Miami Miller School of Medicine, Miami, FL, USA
4:35
H3.03. SELF-LOCOMOTIVE MICROBUBBLER FOR ACTIVE BIOFILM REMOVAL
Hyunjoon Kong, Yongbeom Seo, Yu-Heng Deng, Yu-Tong Hong
University of Illinois at Urbana-Champaign, Urbana, IL, USA
4:45
H3.04. N-ACETYL CYSTEINE TREATMENT DISMANTLES CHRONIC WOUND BIOFILM
Xin Cathy Li, Jane Kim, Jiabin Wu, Yinsheng Wang, Manuela Martins-Green
University of California Riverside, Riverside, CA, USA
4:55
H3.05. Ossabaw Pigs As A Natural Preclinical Model Of Metabolic Syndrome Mediated Impaired Wound Healing
Mithun Sinha1, Nandini Ghosh2, Shomita Steiner1, Amitava Das1, Savita Khanna1, Daniel J. Wozniak2, Sashwati Roy1, Chandan K. Sen1.
1Indiana University, Indianapolis, IN, USA, 2The Ohio State University, Columbus, OH, USA
5:05
H3.06. BIOFILM INFECTION DYSREGULATES CERAMIDE METABOLISM COMPROMISING FUNCTIONAL WOUND CLOSURE OF THE SKIN
Nandini Ghosh1, Mithun Sinha, PhD2, Shomita Steiner, PhD2, Dayanjan S. Wijesinghe, PhD3, Savita Khanna, PhD2, Daniel J. Wozniak, PhD1, Gayle M. Gordillo, MD2, Sashwati Roy, PhD2, Chandan K. Sen, PhD2
1The Ohio State University, Columbus, OH, USA, 2Indiana University, Indianapolis, IN, USA, 3Virginia Commonwealth University, Richmond, VA, USA
 
H4: ACUTE WOUNDS
Moderators: Randolph Stone, PhD; Shanmugasundaram Natesan, PhD
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4:15
H4.01. A MICROBIOME AND METABOLOMIC SIGNATURE OF PHASES OF CUTANEOUS HEALING IDENTIFIED BY PROFILING SEQUENTIAL ACUTE WOUNDS OF HUMAN SKIN
Mohammed Ashrafi, Yun Xu, Howbeer Muhamadali, Iain White, Max Wilkinson, Katherine Holloywood, Mohamed Baguneid, Royston Goodacre, Ardeshir Bayat
The University of Manchester, Manchester, United Kingdom
4:25
H4.02. PILOT CLINICAL STUDY TO DEMONSTRATE THE FEASIBILITY OF MONITORING SUBCUTANEOUS BLOOD FLOW AMONG PERI-OPERATIVE SURGERY PATIENTS
Michael Neidrauer, Alec Lafontant, Vaishali Purohit, Elizabeth Mintz, Kaitlin Kelly, Dhriti Dedhia, Nataly Bingham, Brendan K. McCracken, Leonid Zubkov, Peter A. Lewin, Rose Ann DiMaria-Ghalili, Michael S. Weingarten
Drexel University, Philadelphia, PA, USA
4:35
H4.03. PERIVASCULAR ADIPOSE TISSUE CONTROLS VASODILATATION AND TISSUE PERFUSION IN VIVO THROUGH ADIPOMUSCULAR MICROVASCULAR ANASTOMOSES
Alexander Turaihi, Carla Molthoff, Jasper Koning, Marie Jose Goumans, Connie Jimenez, John Yudkin, Yvo Smulders, Victor van Hinsbergh, Ed Eringa
Amsterdam University Medical Centers, Amsterdam, Netherlands
4:45
H4.04. PROINFLAMMATORY ROLES OF FIBROBLASTS UNDER DEHYDRATION IN OPEN WOUNDS
Ping Xie, David Dolivo, Seok Hong, Robert D. Galiano, Thomas A. Mustoe
Northwestern university, Chicago, IL, USA
4:55
H4.05. SILK FIBROIN-HISTAMINE DRESSING ACCELERATES HEALING IN FULL THICKNESS MICE WOUNDS
Deepanjan Ghosh1, Sudhakar Godeshala1, Jacquelyn Kilbourne1, David J. Dicaudo2, Kaushal Rege1
1Arizona State University, Tempe, AZ, USA, 2Mayo Clinic, Scottsdale, AZ, USA
5:05
H4.06. CLINICAL EVALUATION OF MICROBIAL AND METABOLITE CHANGES IN MINOR WOUND HEALING
Latrisha K. Petersen, InSeok Seo, Erin Zaleski, Parneet Kaur, Kimberly Capone, Melinda Cettina, Paul Zhang, Robert J. Gambogi, Amisha Parikh-Das
Johnson & Johnson, Skillman, NJ, USA
5:30 pm - 8:30 pm
GRAND OPENING OF EXHIBITS/COCKTAIL RECEPTION
WHS Exhibit Booth #532
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DAY 3: THURSDAY, MAY 9, 2019
7:30 am - 9:00 am
INDUSTRY-SUPPORTED SYMPOSIUM BREAKFAST
9:00 am - 9:15 am
BREAK
9:15 am - 10:15 am
WHS SESSION I: Microbial-Host Interactions
Moderators: Elizabeth A. Grice, PhD; Casey Bartow-McKenney, PhD
Speakers: Steven Percival, PhD; Lindsay Kalan, PhD; Diane Newman, PhD
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10:15 am - 10:30 am
BREAK
10:30 am - 11:30 am
WHS SESSION J: Clinical Research in Wound Healing and the FDA
Moderators: Elof Eriksson, MD; Gerald Sylvan Lazarus, MD
Speakers: David J. Margolis, MD; Robert S. Kirsner, MD
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11:30 am - 11:45 am
BREAK
11:45 am - 2:15 pm
12:15 pm - 2:00 pm
WHS MEET THE MENTORS (non-accredited)
Moderator: Lisa Gould, MD, PhD
Speakers: Luisa Ann DiPietro, DDS, PhD; Irena Pastar, PhD
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2:00 pm - 2:15 pm
BREAK
2:15 pm - 3:15 pm
WHS SESSION K: CONCURRENT ORAL ABSTRACTS II (non-accredited)
Oral presentations will feature the highest scoring abstracts submitted to the WHS.
 
K1: STEM CELLS/REGENERATION
Moderators: Mithun Sinha, PhD; Norifumi Urao, PhD
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2:15
K1.01. ADIPOSE STEM CELL TISSUE SOURCE IS ASSOCIATED WITH DIFFERENTIAL EXPRESSION PROFILES IN CELLULAR MRNA AND EXOSOMAL MIRNA
Lauren Mangum1, Randolph Stone, II1, Shanmugasundaram Natesan1, Barbara Christy1, John Clifford2, Raina Kumar2, Andrew Cap1, Rasha Hammamieh2, Robert Christy1
1US Army Institute of Surgical Research, Fort Sam Houston, TX, USA, 2US Army Center for Environmental Health Research, Fort Detrick, MD, USA
2:25
K1.02. WOUND HEALING POTENTIAL OF HUMAN IPSC-DERIVED VASCULAR SMOOTH MUSCLE CELLS
Henry Hsia, Biraja Dash, Ocean Setia, Hassan Peyvandi, Lara Lopes, James Nie, Alan Dardik
Yale School of Medicine, New Haven, CT, USA
2:35
K1.03. METABOLIC ORCHESTRATION OF EPIDERMAL STEM CELLS AND ADIPOCYTES PROMOTES HEALING IN OBESITY WOUND
Ji LIN1, Xiao-ning GAO2
1Institute of Basic Medicine, Chinese PLA General Hospital, Beijing, China, 2Department of Hematology, Chinese PLA General Hospital, Beijing, China
2:45
K1.04. RETRO-ORBITAL INFUSION OF HUMAN MESENCHYMAL STROMAL CELLS ACCELERATES WOUND HEALING THROUGH SYSTEMIC EFFECTS
Nina Kosaric, Wai Srifa, Harriet Kiwanuka, Matthew Porteus, Geoffrey Gurtner
Stanford University, Stanford, CA, USA
2:55
K1.05. FIBROBLASTS: CHRONICALLY BAD BUT NOT SO DOWN IN THE MOUTH
Phil Stephens
Cardiff University, Cardiff, United Kingdom
3:05
K1.06. THE EFFECT OF AN AUTOLOGOUS KERATINOCYTE SPRAY ON HUMAN SKIN WOUND HEALING TRANSCRIPTOME
Kristo Nuutila1, Antti Siltanen2, Matti Korhonen3, Johanna Nystedt3, Jussi Valtonen4, Andrew Lindford4, Jyrki Vuola4, Esko Kankuri2
1Brigham and Women's Hospital, Boston, MA, USA, 2University of Helsinki, Helsinki, Finland, 3Finnish Red Cross Blood Service, Helsinki, Finland, 4Helsinki Burn Center, Helsinki, Finland
 
K2: FIBROSIS/SCARRING II
Moderators: Robert D. Galiano, MD; Rodney Chan, MD
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2:15
K2.01. A THERMOGELLING HYALURONIC ACID VAGINAL STENT TO REDUCE POSTOPERATIVE VAGINAL SCARRING
Omar Wyman1, Swathi Balaji2, Sundeep Keswani2, Julie Hakim2
1University of Oklahoma, Norman, OK, USA, 2Texas Children's Hospital, Houston, TX, USA
2:25
K2.02. PIRFENIDONE ATTENUATES THE PROFIBROTIC CONTRACTILE PHENOTYPE OF HUMAN DERMAL MYOFIBROBLASTS
Adrienne R. Wells, Kai P. Leung
US Army Institute of Surgical Research, Fort Sam Houston, TX, USA
2:45
K2.04. KERATINOCYTE PROLIFERATION CORRELATES WITH THE EXTENT OF SCAR FORMATION
Hui Li1, Swathi Balaji1, Xinyi Wang1, Paul Bollyky2, Manish Butte3, Sundeep Keswani1
1Baylor College of Medicine, Houston, TX, USA, 2Stanford University, Palo Alto, CA, USA, 3UCLA, Los Angeles, CA, USA
2:55
K2.05. SERUM AND WOUND ENVIRONMENT C- REACTIVE PROTEIN, VIABLE BACTERIA AND SICKNESS BEHAVIOR SYMPTOMS IN NON-HEALING WOUNDS
Joyce Stechmiller, RN PhD, Debra Lyon, RN PhD, Daniel Gibson, PhD, Michael Weaver, RN PhD, Joie Whitney, RN PhD, Jung Kim, RN PhD, Gregory Schultz, PhD
University of Florida, Gainesville, FL, USA
3:05
K2.06. EXOSOMES DERIVED FROM DERMAL FIBROBLASTS DEFINE THE INTRINSIC VARIABILITY IN WOUND HEALING RESPONSES
Hima Vangapandu1, Natalie Templeman1, Daniel Colchado1, Alexander Blum1, Hui Li1, Xinyi Wang1, Emily Steen1, Paul Bollyky2, Sundeep Keswani1, Matthew Robertson1, Cristian Coarfa1, Swathi Balaji1
1Baylor College of Medicine, Houston, TX, USA, 2Stanford University, Palo Alto, CA, USA
 
K3: CHRONIC WOUNDS - CLINICAL
Moderators: Allen Holloway, MD; Veronica Haywood, PT
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2:15
K3.01. RESULTS OF THE OPINION SURVEY FROM PEOPLE WITH WOUNDS
Lisa Gould1, Vickie Driver2, Jing Liu3, Peggy Dotson4
1South Shore Health Center for Wound Healing, Weymouth, MA, USA, 2Novartis Institute for Biomedical Research, Cambridge, MA, USA, 3Northwestern University Feinberg School of Medicine, Chicago, IL, USA, 4Health Care Reimbursement Strategy, Wilmington, NC, USA
2:25
K3.02. PERSONALIZED PRESSURE INJURY PREVENTION PLANNING: CLINICAL PRACTICE GUIDELINES, THE ELECTRONIC HEALTH RECORD AND BIG DATA
Kath M. Bogie1, M Kristi Henzel2, GQ Zhang3, Steven Roggenkamp3, Jiayang Sun1, Arielle Bloostein1, Jacinta M. Seton2, Youjun Li1, Mary Ann Richmond2, Monique Washington2
1Case Western Reserve University, Cleveland, OH, USA, 2Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA, 3University of Kentucky, Louisville, KY, USA
2:35
K3.03. RISK FACTORS FOR MAJOR AMPUTATION ON HINDFOOT ULCERS IN HOSPITALIZED DIABETIC PATIENTS
Seung Kyu Han, Jae youn Kim, Ji Won Son, Sik Namgoong
Korea University Guro Hospital, seoul, Korea, Republic of
2:45
K3.04. MONITORING MICROCIRCULATORY BLOOD FLOW IN CHRONIC DIABETIC AND VENOUS ULCERS WITH DIFFUSE CORRELATION SPECTROSCOPY
Michael Neidrauer1, Michael S. Weingarten1, Alec Lafontant1, Keyanna Bynum1, Christine Wojciechowicz1, Elizabeth Mintz1, Leonid Zubkov1, David Margolis2, Rose Ann DiMaria-Ghalili1, Peter A. Lewin1
1Drexel University, Philadelphia, PA, USA, 2University of Pennsylvania, Philadelphia, PA, USA
2:55
K3.05. PHASE 2 TRIAL OF HUMAN UMBILICAL CORD FOR COMPLEX NON-HEALING DIABETIC FOOT ULCERS
Herbert B. Slade, Tommy D. Lee, Nick McCoy, Scheffer Tseng
Tissuetech Inc, Fort Worth, TX, USA
3:05
K3.06. TOWARD AN UNDERSTANDING OF PRESSURE INJURY RISK AND LOCAL AND CIRCULATORY BIOMARKERS
Kath M. Bogie1, M Kristi Henzel2, Mary Ann Richmond2, Nannette Alvarado2, Jen Zindle2, Katie A. Schwartz2, David Lemmer2, Jacinta M. Seton2, Youjun Li1, Jiayang Sun1
1Case Western Reserve University, Cleveland, OH, USA, 2Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA
 
K4: INFLAMMATION/IMMUNITY/AGING
Moderators: Kara L. Spiller, PhD; Jessica Eager, PhD
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2:15
K4.01. LOW MICRORNA-21 IN DIABETIC WOUND MACROPHAGES IMPAIR RESOLUTION OF INFLAMMATION
Amitava Das, Mithun Sinha, Pradipta Banerjee, Nirupam Biswas, Savita Khanna, Chandan K. Sen, Sashwati Roy
Indiana University School of Medicine, Indianapolis, IN, USA
2:25
K4.02. PIRFENIDONE REGULATES LPS MEDIATED HYPER ACTIVATION OF NEUTROPHILS
Shankar J. Evani, Kai P. Leung
USAISR, Fort Sam Houston, TX, USA
2:35
K4.03. DIFFERENTIAL EXPRESSION OF GRANZYME B IN MACROPHAGES
Matthew R. Zeglinski, Christopher T. Turner, David J. Granville
University of British Columbia, Vancouver, BC, Canada
2:45
K4.04. A MODIFIED COLLAGEN DRESSING INDUCES TRANSITION OF INFLAMMATORY TO REPARATIVE PHENOTYPE OF WOUND MACROPHAGES
Amitava Das1, Motaz Abas2, Nirupam Biswas1, Pradipta Banerjee1, Nandini Ghosh2, Savita Khanna1, Edward Stout3, Sashwati Roy1, Chandan K. Sen1
1Indiana University School of Medicine, Indianapolis, IN, USA, 2The Ohio State University, Columbus, OH, USA, 3Southwest technologies Inc, Kansas City, MO, USA
3:05
K4.06. CAVEOLIN-1 PROMOTES BACTERIAL COLONIZATION AND INHIBITION OF WOUND CLOSURE IN AGED HUMAN SKIN
Ivan Jozic, Irena Pastar, Cheyanne R. Head, Robert S. Kirsner, Marjana Tomic-Canic
University of Miami Miller School of Medicine, Miami, FL, USA
3:15 pm - 3:30 pm
BREAK
3:30 pm - 4:30 pm
WHS DAY 3 GENERAL SESSION - Bioengineering and Wound Healing
View Video
Moderators: Praveen R. Arany, DDS, PhD; Alan Wells, MD, DMSc
Speaker: Eric Brey, PhD; Heather Powell, MD; Ardeshir Bayat, MB, BS, PhD
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4:30 pm - 4:45 pm
BREAK
4:45 pm - 5:40 pm
WHS Session L: WOUND HEALING FOUNDATION - 3M FELLOWSHIP LECTURE
Moderators: Manuela Martins-Green, MD; Veronica Haywood, PT
Speaker: Swathi Balaji, PhD
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5:40 pm - 5:45 pm
WHF AWARDS PRESENTATION
5:45 pm - 6:45 pm
WHS BUSINESS MEETING AND MEMBERSHIP PHOTO
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6:45 pm - 7:15 pm
WHS Session M: RAPID FIRE POSTER TALKS
Moderators: Timothy W. King, MD, PhD; Praveen R. Arany, DDS, PhD
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6:48
M1.01. GENE EXPRESSION ANALYSIS OF DIABETIC FOOT ULCER DEBRIDED TISSUE FOR PREDICTING RESPONSIVENESS TO TREATMENTS
Jessica M. Eager1, Michael S. Weingarten, MD2, Will Dampier, PhD3, Kara L. Spiller, PhD1
1School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA, 2Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, USA, 3Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, USA
6:51
M1.02. A PLASMA-ALGINATE COMPOSITE MATERIAL PROVIDES IMPROVED MECHANICAL SUPPORT FOR STEM CELL GROWTH AND DELIVERY
Nicholas E. Clay, Carissa Villanueva, Nicole Wrice, Andrew C. Kowalczewski, Shanmugasundaram Natesan, Robert J. Christy
US Army Institute of Surgical Research, Fort Sam Houston, TX, USA
6:54
M1.03. NOTCH ACTIVATION STIMULATES WOUND HEALING
Liz Quintero, Timothy W. King
University of Alabama At Birmingham, Birmingham, AL, USA
6:57
M1.04. TOPICAL CROMOLYN SODIUM REDUCES POST-BURN HYPERTROPHIC SCARS IN FEMALE RED DUROC PIGS
Jayson W. Jay, Anesh Prasai, Amina El Ayadi, Christian Sommerhalder, Daniel Popp, Evan Ross, Elizabeth Blears, Guillermo Foncerrada, Christian Tapking, David N. Herndon, Celeste C. Finnerty
University of Texas Medical Branch, Galveston, TX, USA
7:00
M1.05. EFFECTS OF A PEER-LED SELF-MANAGEMENT PROGRAM ON PATIENTS WITH DIABETIC FOOT ULCERS
Ye-Na Lee
College of Nursing, Korea University, Goyang-si, Korea, Republic of
7:03
M1.06. IMMUNE CELL ACTIVITY IN HUMAN CUTANEOUS WOUND HEALING AND SKIN SCARRING: A MULTIPLE TIME POINT IMMUNOHISTOCHEMICAL STUDY
Sara Ud-Din1, Douglas McGeorge2, Ardeshir Bayat1
1University of Manchester, Manchester, United Kingdom, 2Nuffield Grosvenor Hospital, Chester, United Kingdom
7:06
M1.07. SMAD7 AMELIORATES TGF?-MEDIATED SKIN INFLAMMATION AND ASSOCIATED WOUND HEALING DEFECTS
Li BIAN, Fulun Li, Shunsuke Iriyama, Zhe Jian, Bin Fan, Jing Jing Luo, Dongyan D Wang, Christian D. Young, Gangwen Han, Xiao-Jing Wang
Univisity Of Colorado Anschutz Medical Campus, Aurora, CO, USA
7:09
M1.08. KNOWLEDGE, ATTITUDES, BELIEFS, AND BEHAVIORS ABOUT ANTIBIOTICS BY PERSONS WITH WOUNDS
Barbara Pieper1, Joanne Sobeck1, Linda Kaljee2, Thomas N. Templin1
1Wayne State University, Detroit, MI, USA, 2Henry Ford Health System, Global Health Initiative, Detroit, MI, USA
7:15 pm - 8:45 pm
WHS AND SAWC SPRING POSTER GALA/AWARDS
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DAY 4: FRIDAY, MAY 10, 2019
7:30 am - 9:00 am
INDUSTRY-SUPPORTED BREAKFAST SYMPOSIA
9:00 am - 9:15 am
BREAK
9:15 am - 10:15 am
WHS Day 4 GENERAL SESSION - NEW FRONTIERS IN FETAL WOUND HEALING
View Video
Moderators: Timothy W. King, MD, PhD; Adrian Barbul, MD
Speaker: Traci A. Wilgus, PhD; Kenneth W. Liechty, MD
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10:15 am - 10:30 am
BREAK
10:30 am - 11:30 am
WHS SESSION N: CONCURRENT ORAL ABSTRACTS III (non-accredited)
Oral presentations will feature the highest scoring abstracts submitted to the WHS.
 
N1: NOVEL THERAPIES
Moderators: Daria A. Narmoneva, PhD; Subhadip Ghatak, PhD
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10:30
N1.01. 3D PATIENT SPECIFIC IMPLANT FOR CRANIOFACIAL RECONSTRUCTION
JongWon Rhie1, Hyunho Han2, Jin Hyung Shim3, Dong Woo Cho4, Chung Hwan Baek5
1The Catholic University of Korea, Seoul St. Mary’s Hospital, Seoul, Korea, Republic of, 2Seoul Asan Medical Center, Seoul, Korea, Republic of, 3Korea Polytechnic University, Seoul, Korea, Republic of, 4Pohang University of Science and Technology, Pohang, Kyungbuk, Korea, Republic of, 5Seoul Samsung Medical Center, Seoul, Korea, Republic of
10:40
N1.02. THE USE OF ACELLULAR DERMAL MATRIX PASTE FOR TREATMENT OF DIABETIC FOOT ULCER
Donghyeok Shin
Konkuk University Medical Center, Seoul, Korea, Republic of
10:50
N1.03. IMPACT OF EXTRACORPOREAL SHOCK WAVE THERAPY ON MICROCIRCULATION IN DIABETIC FEET: A PILOT STUDY
Seung Kyu Han, Jae youn Kim,, Ji Won Son, sik Namgoong
Korea University Guro Hospital, seoul, Korea, Republic of
11:00
N1.04. TREATMENT OF FULL-THICKNESS WOUNDS WITH MICROFRAGMENTED ADIPOSE TISSUE AND PLASMA-BASED HYDROGELS
David Larson, Randolph Stone, II, John Wall, Shanmugasundaram Natesan, Robert Christy
US Army Institute of Surgical Research, Fort Sam Houston, TX, USA
11:10
N1.05. PRESERVING THE LENGTH OF A DIABETIC LIMB BY MICROSURGICAL TECHNIQUE
Hyunsuk Peter Suh, Professor
Korea University Medical Center, Seoul, South Korea
 
N2: EPITHELIALIZATION/ANGIOGENESIS/OXYGEN/HYPOXIA
Moderators: Harvey N. Himel, MD, MPH; Nandini Ghosh, PhD
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10:30
N2.01. COMPROMISED ANGIOGENESIS, INCREASED VESSEL PERMEABILITY, AND DECREASED PERICYTE COVERAGE IN IMPAIRED DIABETIC SKIN WOUNDS
Uzoagu A. Okonkwo1, Lin Chen1, Da Ma2, Veronica A. Haywood1, May Barakat1, Norifumi Urao1, Luisa A. DiPietro1
1University of Illinois at Chicago, Chicago, IL, USA, 2Guanghua School of Stomatology, SunYat-sen University, Guangzhou, China
10:40
N2.02. IN VIVO EVALUATION OF ANGIOGENIC PROPERTIES OF A DEHYDRATED AMNION CHORION MEMBRANE
John McQuilling1, MaryRose Kammer2, Kelly Kimmerling1, Katie Mowry1
1Organogenesis Inc, Birmingham, AL, USA, 2Organogenesis, Birmingham, AL, USA
10:50
N2.03. MIR-193B-3P SUPPRESSES CELLULAR MIGRATION AND CONTRIBUTES TO IMPAIRED WOUND CLOSURE IN DIABETIC FOOT ULCERS
Irena Pastar1, Ivan Jozic1, Horacio A. Ramirez1, Nkemcho Ojeh2, Rivka Stone1, Tongyu Cao Wikramanayake1, Robert S. Kirsner1, Marjana Tomic-Canic1
1University of Miami Miller School of Medicine, Miami Beach, FL, USA, 2Faculty of Medical Sciences, the University of the West Indies, Bridgetown, Barbados
11:00
N2.04. COLLAGEN MATRICES AND AUTOLOGOUS CELLS SUSPENSION DIFFERENTIALLY INFLUENCE RE-EPITHELIALIZATION AT 2 WEEKS IN A PORCINE WOUND MODEL
J Genevieve Park, PhD, MD1, Sita M. Damaraju, PhD2, Benjamin R. Mintz, PhD2, Ankur S. Gandhi, PhD2, Sunil Saini, PhD2, Ronald Ingram, PhD2, Joseph A. Molnar, PhD, MD1
1Wake Forest University School of Medicine, Winston-Salem, NC, USA, 2Integra Lifesciences, Plainsboro, NJ, USA
11:10
N2.05. MIR-210 ENCAPSULATED EXTRACELLULAR VESICLES CONTRIBUTES TO ISCHEMIC INJURY OF THE SKIN
Ayan Biswas, Subhadip Ghatak, Mohamed El Masry, Savita Khanna, Sashwati Roy, Chandan K. Sen
Indiana University, Indianapolis, IN, USA
11:20
N2.06. NOVEL IMPLANTABLE BIOSENSORS FOR LIFETIME-BASED MONITORING OF OXYGENATION TO PREDICT WOUND HEALING
Preet Patel1, Mahmoud Ibrahim2, Ryan Schweller2, Bruce Klitzman2, Mohamid Ibrahim2
1Duke University School of Medicine, Durham, NC, USA, 2Duke University Department of Surgery, Duke University Medical Center, Durham, NC, USA
 
N3: CHRONIC WOUNDS - BASIC SCIENCE
Moderators: Rummana Aslam, PhD; Luris C. De Calero MD
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10:30
N3.01. OVEREXPRESSION OF LNCRNA LETHE ENHANCES DIABETIC WOUND HEALING
Junwang Xu, Junyi Hu, Carlos Zgheib, Kenneth Liechty
University of Colorado, Aurora, CO, USA
10:40
N3.02. COMPARATIVE GLYCOMICS OF DIABETIC AND NON- DIABETIC SKIN REVEAL SIGNIFICANT DIFFERENCESDURING WOUND HEALING
Veronica R. Haywood1, Sylvain D. Lehoux2, Emily E. Rouse2, Karen Colley1, Luisa A. DiPietro1
1UIC, Chicago, IL, USA, 2Beth Israel Deaconess, Boston, MA, USA
10:50
N3.03. Myostatin-regulated Muscle Regeneration In Compressed Rat Skin
Takeo Minematsu, Sanai Tsunokuni, Ayano Nakai, Tamae Urai, Toshihiro Tsukatani, Hiromi Sanada
The University of Tokyo, Tokyo, Japan
11:00
N3.04. IN VITRO BIOACTIVITY OF TRI-LAYER PLACENTAL ALLOGRAFT MEMBRANE
Sita M. Damaraju, Paul Bonvallet, Heli Modi, Morakot Likhitpanichkul, Ankur Gandhi, Sunil Saini
Integra Lifesciences, Corp, Plainsboro, NJ, USA
11:10
N3.05. MATRIX CHANNELS IMPROVE AUTOGRAFT TAKE IN A SINGLE STAGE PROCEDURE
Angana Kharge, PhD, Ankur Gandhi, PhD, Sunil Saini, PhD
Integra Lifesciences, Plainsboro, NJ, USA
11:20
N3.06. WOUND HEALING ACTIVITY OF HUMAN UMBILICAL CORD BLOOD-DERIVED MESENCHYMAL STEM CELLS ON DIABETIC WOUND
Jae-A Jung, MD, PhD, Kyung-Chul Moon, PhD
Korea University Medical Center, Seoul, South Korea
 
N4: BURN WOUNDS/ECM
Moderators: Anie Philip, PhD; Yasser Almadani, PhD
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10:30
N4.01. OPTIMIZATION OF DEBRIDEMENT DEPTH THAT RESULTS IN COMPLETE GRAFT TAKE FOR PORCINE BURN WOUNDS
Randolph Stone, II, David Larson, John Wall, Christine Kowalczewski, Shanmugasundaram Natesan, Robert Christy
US Army Institute of Surgical Research, Fort Sam Houston, TX, USA
10:40
N4.02. TRANSCRIPTOMIC ASSESSMENT OF THE P53 SIGNALING PATHWAY IN THE BURN WOUND ZONE OF STASIS
Gaurav Garg, Abdulnaser Alkhalil, Bonnie Carney, Robert Smith, Kyle Monger, Lauren Moffatt, Jeffrey Shupp
The Burn Center, MedStar Washington Hospital Center, Washington, DC, USA
10:50
N4.03. INCREASED EXPRESSION OF PRO-INFLAMMATORY CYTOKINES AND PERIOSTIN IN BURN ESCHAR PERICYTES
Alexander Evdokiou1, Stephanie Gierek1, Onur Kanisicak2, Richard Bodnar3, Latha Satish1
1Shriners Hospitals for Children-Cincinnati, Cincinnati, OH, USA, 2Department of Pathology and Laboratory Medicine, University of Cincinnati, College of Medicine, Cincinnati, OH, USA, 3Veterans Affairs Medical Center, Pittsburgh, PA, USA
11:00
N4.04. TOPICALLY APPLIED MORPHINE-LOADED KERATIN HYDROGELS ON WOUND HEALING IN A PORCINE BURN MODEL
Christine Kowalczewski1, Nicholas Clay1, Nicole Wrice1, Bopaiah Cheppudira1, John Clifford2, Robert Christy1
1USAISR, Fort Sam Houston, TX, USA, 2USACEHR, Fort Detrick, MD, USA
11:10
N4.05. USE OF AUTOLOGOUS SKIN COLUMNS IN PORCINE DEEP-PARTIAL THICKNESS BURN WOUND HEALING
Anders Carlsson, Tyler Everett, Kai Leung, Rodney Chan
US Army Institute of Surgical Research, San Antonio, TX, USA
11:30 am
WHS MEETING ADJOURNS
11:45 am - 2:15 pm
LUNCH WITH EXHIBITORS
Alamo
Cactus
River Walk
Spanish Tiles