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Wound Healing Society Virtual
2020 Virtual Oral Abstracts

Wound Healing Society Virtual


WHS SESSION H: CONCURRENT ORAL ABSTRACTS I (non-accredited)
ACUTE WOUNDS AND BURN WOUNDS (H1)
H1.01. PRELIMINARY ANALYSIS OF A PHASE 3 OPEN-LABEL, CONTROLLED, RANDOMIZED TRIAL EVALUATING THE EFFICACY AND SAFETY OF A BIOENGINEERED REGENERATIVE SKIN CONSTRUCT IN PATIENTS WITH DEEP PARTIAL-THICKNESS THERMAL BURNS
James H. Holmes1, Jeffrey W. Shupp2, David Smith3, Victor Joe4, Joshua Carson5, Jeffrey Litt6, Steven Kahn7, Tracee Short8, Leopoldo Cancio9, Julie Rizzo10, Jeffrey Carter11, Kevin Foster12, Janice Smiell13, Angela Lf Gibson14
1Department of Surgery, Wake Forest University School of Medicine, Winston Salem, NC, USA, 2Department of Surgery, Medstar Washington Hospital Center, Washington DC, WA, USA, 3Department of Plastic Surgery, University of South Florida, Tampa, FL, USA, 4Department of Surgery, University of California at Irvine, Irvine, CA, USA, 5Department of Surgery, University of Florida, Gainesville, FL, USA, 6Department of Surgery, University of Missouri Health Care, Columbia, MT, USA, 7Department of Surgery, University of South Alabama Medical Center, Mobile, AL, USA, 8Department of Surgery, Baton Rouge General Medical Center, Baton Rouge, LA, USA, 9United States Army Institute of Surgical Research, Fort Sam Houston, TX, USA, 10United States Army Institute of Surgical Research, Joint Base, San Antonio, TX, USA, 11Department of Surgery, Louisiana State University School of Medicine, University Medical Center New Orleans, New Orleans, LA, USA, 12Department of Surgery, The Arizona Burn Center at MIHS, Phoenix, AZ, USA, 13Mallinckrodt Pharmaceuticals, Bedminster, NJ, USA, 14Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
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H1.03. WOUND HEALING MACROPHAGES: THE INTERVENTION OF ATP TO STIMULATE PRO-WOUND HEALING PHENOTYPES
Harshini Sarojini, Sarah Eichenberger, Sufan Chien
University of Louisville, Louisville, KY, USA
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H1.06. THE POLARIZATION OF TH2 RESPONSE IMPROVES THE HEALING OF DEEP PARTIAL-THICKNESS BURNS
Edna A. Mandujano, YI1, Francisco González1, Rosa M. Salgado1, Gerardo Arrellín2, Edgar Krötzsch1
1Instituto Nacional de Rehabilitación, Mexico, Mexico, 2Universidad Autónoma de Morelos, Mexico, Mexico
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INFLAMMATORY AND IMMUNE RESPONSE (H2)
H2.02. FAVORABLE MODULATION OF INFLAMMATION AND IMMUNITY IS ACHIEVED WITH BOTH SINGLE AND TRI-LAYER AMNIOTIC MEMBRANE ALLOGRAFTS
Victoria Stefanelli, Paul Bonvallet, Sita Damaraju, Qiaoling Lin, Heli Modi, Sunil Saini, Ankur Gandhi
Integra LifeSciences, Plainsboro, NJ, USA
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NOVEL THERAPEUTICS AND DIAGNOSTICS I (H3)
H3.01. A NON-CONTACT DEVICE FOR QUICK SCREENING OF WOUND INFECTIONS IN CHRONIC WOUND PATIENTS
Jon Senkowsky1, Hong Vu2, Ashwin Nair2, Lan Tran2, Suvra Pal3, Liping Tang2, Wenjing Hu2
1Texas Health Physician's group, Arlington, TX, USA, 2Progenitec Inc., Arlington, TX, USA, 3University of Texas at Arlington, Arlington, TX, USA
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H3.03. THE USE OF INDOCYANINE GREEN FLUORESCENCE IN A PRECLINICAL MODEL OF HUMAN WOUND HEALING
Aos Karim1, Aiping Liu1, Christie Lin2, Adam Uselmann2, Kevin Eliceiri1, Matthew Brown1, Angela Gibson1
1University of Wisconsin, Madison, WI, USA, 2OnLume, Madison, WI, USA
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H3.04. GLUTATHIONE CONJUGATED HYDROGELS: SIMPLE, FLEXIBLE VEHICLES FOR LOCAL THERAPY
Karol Sokolowski, Hai Pham, Eric R. Wenzler, Richard A. Gemeinhart
University of Illinois at Chicago, Chicago, IL, USA
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H3.05. DETECTION OF NECROSIS AVIDITY USING INDOCYANINE GREEN FLUORESCENCE IN HUMAN WOUND HEALING
Aos Karim1, Kishan Thadikonda1, Christie Lin2, Adam Uselmann2, Kevin Elicieiri1, Samuel Poore1, Angela Gibson1
1University of Wisconsin, Madison, WI, USA, 2OnLume, Madison, WI, USA
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FIBROSIS AND SCARRING I: SIGNALING AND BIOMARKERS (H4)
H4.02. INHIBITING MECHANOTRANSDUCTION SIGNALING CHANGES FIBROBLAST HETEROGENEITY AND PROMOTES TISSUE REGENERATION IN HEALING WOUNDS
Kellen Chen, Sun Hyung Kwon, Dominic Henn, Britta A. Kuehlmann, Clark A. Bonham, Jagannath Padmanabhan, Chikage Noishiki, Janos Barrera, Michael T. Longaker, Michael Januszyk, Geoffrey C. Gurtner
Stanford University, Stanford, CA, USA
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H4.06. REGULATION OF PULMONARY FIBROSIS BY CD109 IN A MURINE MODEL
Maha Alsharqi, Liqin Xu, Meryem Blati, Anie Philip Mcgill
University, Montreal, QC, Canada
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WHS SESSION J: CONCURRENT ORAL ABSTRACTS II
BIOENGINEERING (J1)
J1.06. A NOVEL MURINE DISTRACTION DEVICE INVESTIGATING LONG BONE REGENERATION
Harsh N. Shah, Ankit Salhotra, Michael T. Lopez, Derrick C. Wan, Michael T. Longaker
Stanford University, Stanford, CA, USA
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INFECTION AND BIOFILM (J2)
J2.03. INVESTIGATING BACTERIAL-FUNGAL INTERACTIONS WITHIN CHRONIC WOUND MICROBIOMES
Alex Cheong, Chad Johnson, PhD, Hanxiao Wan, Jeniel Nett, MD, PhD, Lindsay Kalan, PhD
University of Wisconsin-Madison, Madison, WI, USA
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J2.06. HIGH-THROUGH PHENOTYPING OF STAPHYLOCOCCUS AUREUS ISOLATES FROM DIABETIC FOOT ULCERS REVEALS VIRULENCE BEHAVIORS ASSOCIATED WITH CLINICAL OUTCOMES
Amelia R. McCready-Vangi1, Amy E. Campbell1, Sue E. Gardner2, Elizabeth A. Grice1
1University of Pennsylvania, Philadelphia, PA, USA, 2University of Iowa, Iowa City, IA, USA
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ANGIOGENESIS (J3)
J3.01. SINGLE-CELL RNA-SEQUENCING IDENTIFIES NOVEL MOLECULAR TARGETS OF ENDOTHELIAL MICRORNA-200B IN ISCHEMIC WOUND
Kanhaiya Singh, Edward Hernandez, Manishekar Kumar, Yashika Rustagi, Ahmed Abouhashem, Sujit Mohanty, Savita Khanna, Sashwati Roy, Chandan K. Sen
Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA
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J3.03. NRF2 MEDIATES ANGIOGENIC FUNCTION OF ENDOTHELIAL CELLS THROUGH REGULATION OF CXCR4/SDF-1 AXIS
Jasmine Lee1, Alvaro Villareal Ponce1, Joshua A. David2, Joseph F. Kuhn1, Daniel J. Ceradini1
1NYU Langone Medical Center, New York, NY, USA, 2University of Pittsburgh, Pittsburgh, PA, USA
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J3.04. THE EFFECTS OF M1 MACROPHAGE ACTIVATION ON M1-TO-M2 PHENOTYPIC SWITCHING
Erin M. O'Brien, Kara L. Spiller, PhD
Drexel University, Philadelphia, PA, USA
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J4.01. MEVASTATIN FOR TOPICAL USE IN DIABETIC FOOT ULCERS TO ACCELERATE WOUND CLOSURE BY INHIBITION OF CAVEOLIN-1 AND RESTORATION OF EGF SIGNALING
Andjela N. Egger, Andrew P. Sawaya, Ivan Jozic, Rivka C. Stone, Irena Pastar, Marjana Tomic-Canic
Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
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J4.03. GENE EXPRESSION ANALYSIS OF DIABETIC FOOT ULCER DEBRIDED TISSUE TO STANDARD AND ADVANCED TREATMENTS
Jessica M. Eager1, Michael S. Weingarten, MD2, Kara L. Spiller, PhD1
1Drexel University, Philadelphia, PA, USA, 2Drexel University College of Medicine, Philadelphia, PA, USA
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J4.06. DEFEROXAMINE IMPROVES WOUND HEALING IN A MOUSE MODEL OF DELAYED HEALING FROM PRESSURE INJURY
Lisa Tucker-Kellogg1, N. Jannah M. Nasir1, Johannes A. Heemskerk1, Ralph Bunte1, Paul Matsudaira2, Peter T.C. So3
1Duke-NUS Medical School, Singapore, Singapore, 2National University of Singapore, Singapore, Singapore, 3MIT, Cambridge, MA, USA
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WHS SESSION M: RAPID FIRE POSTER TALKS
M1.01. HYPOPIGMENTED HYPERTROPHIC SCAR CAN BE TREATED WITH SYNTHETIC ALPHA MELANOCYTE STIMULATING HORMONE
Bonnie C. Carney1, Lauren T. Moffatt2, Cynthia M. Simbulan-Rosenthal1, Dean S. Rosenthal1, Jeffrey W. Shupp2
1Department of Biochemistry, Georgetown University School of Medicine, Washington, DC, USA, 2Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, USA
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M1.03. FLUID FLOW IN TUMESCED SUBCUTANEOUS PIG TISSUE
John P. Koulakis, Joshua Rouch, Nhan Huynh, Holden H. Wu, James C. Y. Dunn, Seth Putterman
UCLA, Los Angeles, CA, USA
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WHS SESSION N: CONCURRENT ORAL ABSTRACTS III (non-accredited)
STEM CELLS, REGENERATION, AND AGING (N1)
N1.01. REDUCTION OF SENESCENT CELLS IMPROVES HEALING IN AN IN VITRO MODEL OF AGED HEALING
Upasana Niyogi, Mark A. Carlson
University of Nebraska Medical Center, Omaha, NE, USA
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N1.06. CLINICAL EFFICACY OF NEW GENERATION VASCULAR AND TISSUE REGENERATIVE CELL (MNC-QQ) THERAPY FOR NON-HEALING ISCHEMIC ULCER
Rica Tanaka, Taro Fukuta, Satoshi Fujimura, Kayo Arita, Rie Hirano, Hiroshi Mizuno
Juntendo University School of Medicine, Tokyo, Japan
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CHRONIC WOUNDS: CLINICAL RESEARCH (N2)
N2.05. EFFECTIVENESS OF AMNIOTIC MEMBRANE AND UMBILICAL CORD PARTICULATE FOR PRESSURE ULCERS: A RETROSPECTIVE STUDY
Anne T. Mancino, Alison Acott, Kathryn P. Brinegar
CAVHS, Little Rock, AR, USA
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N2.06. RISK FACTORS FOR MAJOR AMPUTATION IN HOSPITALIZED DIABETIC PATIENTS WITH FOREFOOT ULCERS
Seung-Kyu Han, Kyung-Chul Moon
Korea University Guro Hospital, Seoul, Korea, Republic of
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THERAPEUTICS AND DIAGNOSTICS II (N3)
N3.06. FATTY ACID POTASSIUM HAD BENEFICIAL BACTERICIDAL AND BIOFILMS REMOVAL EFFECTS WITH REDUCED CYTOTOXICITY OF FIBROBLASTS AND KERATINOCYTES
Sadanori Akita1, Takayoshi Kawahara2, Akihiro Masunaga3, Miki Takita3, Hayato Morita3, Tadayuki Tsukatani4, Kouji Nakazawa5, Daisuke Go5
1Fukuoka University, Fukuoka, Japan, 2Shabondama, KItakyushu, Japan, 3Shabondama, Kitakyushu, Japan, 4Fukuoka Industrial technology Center, Fukuoka, Japan, 5Kitakyushu Municipal University, Fukuoka, Japan
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