Annual Meeting Program
DAY 1: TUESDAY, MAY 14, 2024
8:00 AM - 8:15 AM
WHS WELCOME AND INTRODUCTION
Moderators: Traci Wilgus, PhD; Rivkah Isseroff, MD; Timothy Koh, PhD
Moderators: Traci Wilgus, PhD; Rivkah Isseroff, MD; Timothy Koh, PhD
8:15 AM - 9:15AM
WHS SESSION A: Thomas K. Hunt Honorary Lecture
Moderators: Traci Wilgus, PhD; Sundeep Keswani, MD
This session is named in honor one of the founding members of the Wound Healing Society, Dr. Thomas K. Hunt. The selected speaker will be an individual that has made significant scientific and/or clinical contributions to a field relevant to wound healing. In this session, the speaker will provide an overview of their work and highlight how their findings may advance the field of wound healing.
Moderators: Traci Wilgus, PhD; Sundeep Keswani, MD
This session is named in honor one of the founding members of the Wound Healing Society, Dr. Thomas K. Hunt. The selected speaker will be an individual that has made significant scientific and/or clinical contributions to a field relevant to wound healing. In this session, the speaker will provide an overview of their work and highlight how their findings may advance the field of wound healing.
Speaker:
 |
Wound Repair, Fibroblast Heterogeneity, and Regeneration Michael Longaker, MD, MBA, DSc (hon) FACS |
9:15 AM - 9:30 AM
BREAK
9:30 AM - 10:30 AM
WHS SESSION B: Fibroblast Heterogeneity and ECM
Moderators: Timothy King, MD, PhD; Mateusz Wietecha, DMD, PhD
Fibroblasts are a critical cell type in healing wounds. They are responsible for restoring the extracellular matrix (ECM) after injury, but they usually do so in a manner that results in a fibrotic scar. Recently, significant advances have improved our understanding of fibroblast behavior and the heterogeneous nature of fibroblasts within healing wounds. This session will discuss the latest findings related to fibroblast heterogeneity and the regulation of ECM production by fibroblasts.
Moderators: Timothy King, MD, PhD; Mateusz Wietecha, DMD, PhD
Fibroblasts are a critical cell type in healing wounds. They are responsible for restoring the extracellular matrix (ECM) after injury, but they usually do so in a manner that results in a fibrotic scar. Recently, significant advances have improved our understanding of fibroblast behavior and the heterogeneous nature of fibroblasts within healing wounds. This session will discuss the latest findings related to fibroblast heterogeneity and the regulation of ECM production by fibroblasts.
Speakers:
 |
Spatial-Temporal Dynamics of Fibroblast States During Skin Wound Repair Raul Ramos, PhD |
 |
Fibroblast-Macrophage Interactions Regulate Acute Skin Repair Brett Shook, PhD |
10:30 AM - 11:30 AM
WHS SESSION C: Tissue Regeneration
Moderators: Min Zhao, MD, PhD; Subhadip Ghatak, PhD
The ideal response to tissue injury is regeneration. While adult mammals have a limited capacity for regeneration and typically heal with fibrotic scars, there are a number of animal models that can be used to understand the process of regeneration. This session will discuss current state-of-the-art research in unique models of tissue regeneration and highlight the latest ideas on how to promote regeneration in injured tissues.
Moderators: Min Zhao, MD, PhD; Subhadip Ghatak, PhD
The ideal response to tissue injury is regeneration. While adult mammals have a limited capacity for regeneration and typically heal with fibrotic scars, there are a number of animal models that can be used to understand the process of regeneration. This session will discuss current state-of-the-art research in unique models of tissue regeneration and highlight the latest ideas on how to promote regeneration in injured tissues.
Speakers:
 |
Dissecting The Molecular Signals Underlying Skin Regeneration Versus Scar Forming Repair Jeff Biernaskie, PhD |
 |
The Role of Hyaluronan/Periostin Crosstalk In Dermal Inflammation and Scarring Sundeep Keswani, MD |
11:30 AM - 11:45 AM
BREAK
11:45 AM - 12:45 PM
WHS SESSION D: Wacky Wounds
Moderators: Carlos Zgheib, PhD, MS; Rivka Stone, MD, PhD
Wounds typically heal through an ordered process of hemostasis, inflammation, proliferation and remodeling. Disruption of this ordered progression can lead to an atypical healing process that can be clinically problematic. This session will discuss pathological consequences of a dysregulated healing process evident in some clinically relevant atypical wounds.
Moderators: Carlos Zgheib, PhD, MS; Rivka Stone, MD, PhD
Wounds typically heal through an ordered process of hemostasis, inflammation, proliferation and remodeling. Disruption of this ordered progression can lead to an atypical healing process that can be clinically problematic. This session will discuss pathological consequences of a dysregulated healing process evident in some clinically relevant atypical wounds.
Speakers:
 |
Sticks and Stones Can Cause New Bone; Tissue Injury Can Stimulate Ectopic Bone Formation Benjamin Levi, MD |
 |
Hidradenitis Suppurativa - The Ultimate Inflammatory Ulcer Hadar Lev-Tov, MD |
12:45 PM - 2:00 PM
WOUNDSHARK INNOVATION COMPETITION LUNCH
Moderators: Vickie Driver, DPM; Mitchell Sanders, PhD, Rivkah Isseroff, MD; Timothy Koh, PhD
Following a brief introduction of the program, the competition will focus on two areas of wound research. A translational track (clinical and research studies) and a commercial track (products and devices). Each participant will have 5 minutes to present their work in a single PowerPoint slide. Presentations will be followed by Q&A from judges and a winner will be selected. This session is a WHS Members Only Event. Lunch will be provided.
Moderators: Vickie Driver, DPM; Mitchell Sanders, PhD, Rivkah Isseroff, MD; Timothy Koh, PhD
Following a brief introduction of the program, the competition will focus on two areas of wound research. A translational track (clinical and research studies) and a commercial track (products and devices). Each participant will have 5 minutes to present their work in a single PowerPoint slide. Presentations will be followed by Q&A from judges and a winner will be selected. This session is a WHS Members Only Event. Lunch will be provided.
2:00 PM - 3:00 PM
WHS SESSION E: Infection and Microbiome
Moderators: Lindsay Kalan, PhD; Irena Pastar, PhD
The presence of microbes is known to influence the wound healing process. The number and type of microbes present in a healing wound, their metabolic products, as well as microbe-microbe interactions and microbe-host interactions can significantly modify the rate of repair and alter long-term outcomes. This session will discuss the latest work on wound infection and prevention and will provide up-to-date information about advances in wound infection research.
Moderators: Lindsay Kalan, PhD; Irena Pastar, PhD
The presence of microbes is known to influence the wound healing process. The number and type of microbes present in a healing wound, their metabolic products, as well as microbe-microbe interactions and microbe-host interactions can significantly modify the rate of repair and alter long-term outcomes. This session will discuss the latest work on wound infection and prevention and will provide up-to-date information about advances in wound infection research.
Speakers:
 |
Infection in Diabetic Wounds: Causes & Emerging Therapies Sasha Shafikhani, PhD |
 |
Bacteriophages and Wound Healing Paul Bollyky, MD, DPhil |
3:00 PM - 3:15 PM
BREAK
3:15 PM - 4:15 PM
WHS SESSION F: Wound Inflammation
Moderators: Luisa DiPietro, DDS, PhD; Jordan Yaron, PhD
Inflammation, and the associated recruitment and activation of immune cells, play an important role in the wound healing process. Inflammation can be critical for preventing infection and the type and duration of inflammation can also influence other aspects of healing such as angiogenesis, the formation of granulation tissue, the speed of closure and the amount of scar tissue that will be produced. The speakers in this session will discuss recent developments related to inflammation and wound healing.
Moderators: Luisa DiPietro, DDS, PhD; Jordan Yaron, PhD
Inflammation, and the associated recruitment and activation of immune cells, play an important role in the wound healing process. Inflammation can be critical for preventing infection and the type and duration of inflammation can also influence other aspects of healing such as angiogenesis, the formation of granulation tissue, the speed of closure and the amount of scar tissue that will be produced. The speakers in this session will discuss recent developments related to inflammation and wound healing.
Speakers:
 |
Mechanical Conditioning Of Mesenchymal Stromal Cells For Wound Healing Therapies Boris Hinz, PhD |
 |
Leveraging Dynamic Changes in Macrophage Phenotype For Chronic Wound Healing Kara Spiller, PhD |
4:15 PM - 4:30 PM
BREAK
4:30 PM - 5:30 PM
WHS SESSION G: International Session - Global Challenges in Wound Education
Moderators: Lisa Gould, MD, PhD; Ira Herman, PhD; Susan Volk, VMD, PhD
The impact of non-healing wounds has an enormous global burden. While there are many educational opportunities for wound care professionals, there are major gaps in basic wound education and management that are global and trans-disciplinary. Early intervention has the potential to prevent the development of chronic wounds, reduce hospitalizations, and reduce the financial and emotional toll of these wounds on the globe’s healthcare delivery systems. Thus, it is imperative that trainees across the care continuum receive all the tools needed for optimization of wound care. This international session will explore the gaps, inconsistencies, and success stories of expanding the knowledge base while integrating wound care into the healthcare professionals’ basic curriculum.
Moderators: Lisa Gould, MD, PhD; Ira Herman, PhD; Susan Volk, VMD, PhD
The impact of non-healing wounds has an enormous global burden. While there are many educational opportunities for wound care professionals, there are major gaps in basic wound education and management that are global and trans-disciplinary. Early intervention has the potential to prevent the development of chronic wounds, reduce hospitalizations, and reduce the financial and emotional toll of these wounds on the globe’s healthcare delivery systems. Thus, it is imperative that trainees across the care continuum receive all the tools needed for optimization of wound care. This international session will explore the gaps, inconsistencies, and success stories of expanding the knowledge base while integrating wound care into the healthcare professionals’ basic curriculum.
Speakers:
 |
The importance of Wound Diagnosis In Wound Education Kirsi Isoherranen, PhD |
 |
ECHO Skin and Wound Care: Moving Knowledge, Not Patients Gary Sibbald, MD |
6:30 PM - 9:30 PM
SOCIAL EVENT FOR WHS MEMBERS
Registered WHS members are invited to attend. Location TBD
Registered WHS members are invited to attend. Location TBD
DAY 2: WEDNESDAY, MAY 15, 2024
7:00 AM - 9:00 AM
WHS Committee Meetings
9:00 AM - 9:15 AM
BREAK
9:15 AM - 10:30 AM
SAWC SPRING OPENING CEREMONY AND KEYNOTE ADDRESS
10:30 AM - 10:45 AM
BREAK
10:45 AM - 11:45 AM
WHS SESSION H: Health Disparities in Wound Healing
Moderators: Dorothy Supp, PhD; E. Foy White-Chu, MD
Socioeconomic and racial disparities affect the burden of various diseases including the ability to obtain optimal healthcare. For wound healing, these disparities including access to effective education and care, likely play a role in the ability to heal wounds effectively and prevent their recurrence. This session will highlight the latest research related to health disparities in wound healing, including surgical outcomes and risk of amputation.
Moderators: Dorothy Supp, PhD; E. Foy White-Chu, MD
Socioeconomic and racial disparities affect the burden of various diseases including the ability to obtain optimal healthcare. For wound healing, these disparities including access to effective education and care, likely play a role in the ability to heal wounds effectively and prevent their recurrence. This session will highlight the latest research related to health disparities in wound healing, including surgical outcomes and risk of amputation.
Speakers:
 |
Addressing Barriers to Care to Optimize Treatment of Patients with Diabetic Foot Disease Maya Fayfman, MD |
 |
Addressing Limb-Loss Disparities With Community-Engaged Research Samantha Minc, MD, MPH |
11:45 AM - 12:00 PM
BREAK
12:00 PM - 1:30 PM
WHS Committee Meetings
1:30 PM - 1:45 PM
BREAK
1:45 PM - 4:00 PM
WHS SESSION I: Young Investigators Symposium
Moderators: Traci Wilgus, PhD; Willeke Daamen, PhD; Piul Rabbani, PhD
In this session, young investigators involved in cutting-edge research will compete for the WHS Young Investigator Award. The winner will present his/her work at the ETRS meeting. Oral presentations will feature the top eight abstracts submitted to the WHS by young investigators as well as the winner of the ETRS Young Investigator Award.
Moderators: Traci Wilgus, PhD; Willeke Daamen, PhD; Piul Rabbani, PhD
In this session, young investigators involved in cutting-edge research will compete for the WHS Young Investigator Award. The winner will present his/her work at the ETRS meeting. Oral presentations will feature the top eight abstracts submitted to the WHS by young investigators as well as the winner of the ETRS Young Investigator Award.
I.01. Single-Cell Transcriptomics Reveals Reduction Of A Population Of Monocyte-Derived Dendritic Cells Associated With Impaired Healing In Diabetic Wounds Of Mice
Jingbo Pang1, Mehrdad Zandigohar2, Yang Dai2, Timothy J. Koh1
1Kinesiology & Nutrition, University of Illinois at Chicago, Chicago, IL, United States 2Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States
Jingbo Pang1, Mehrdad Zandigohar2, Yang Dai2, Timothy J. Koh1
1Kinesiology & Nutrition, University of Illinois at Chicago, Chicago, IL, United States 2Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States
I.02. Macrophage RNA Binding Protein Pcbp2 Interacts With Pre-Mir-21 In Keratinocyte-Derived Exosome For Resolution Of Inflammation
Anita Yadav1, Anu Sharma1, Chandan K. Sen1, Sashwati Roy1, Subhadip Ghatak1
1Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Anita Yadav1, Anu Sharma1, Chandan K. Sen1, Sashwati Roy1, Subhadip Ghatak1
1Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States
I.03. Using Microbial Transcriptional Profiles As A Biomarker For Diabetic Wound Healing
Alex Cheong1, Oluchi Aroh2, Caitlin Sande2, Jessica Irvine1, Anna Nora1, Meghan Brennan1, Lindsay Kalan2
1University of Wisconsin, Madison, WI, United States. 2McMaster University, Hamilton, ON, Canada
Alex Cheong1, Oluchi Aroh2, Caitlin Sande2, Jessica Irvine1, Anna Nora1, Meghan Brennan1, Lindsay Kalan2
1University of Wisconsin, Madison, WI, United States. 2McMaster University, Hamilton, ON, Canada
I.04. Perinatal Upregulation of CCL11 In Skin Fibroblasts Is Essential For Subcutaneous Adipogenesis And Wound Healing
Rahul Debnath, Zhaoxu Chen, Kang Ko
Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States
Rahul Debnath, Zhaoxu Chen, Kang Ko
Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States
I.05. Host-Biofilm Interaction derived Oxylipin Impairs Diabetic Foot Ulcer Healing by Targeting T-Cell Immune Checkpoint Pathway
Sunil Kumar1, Miguel Jorge1, Imran Khan1, Ethan Rinne1, Bryce Hockman1,2, Kaitlyn Depinet2, Beth Altenburger2, Jaimee Hann2, Gregory Westin2,3, Mithun Sinha1
1Department of Surgery, Division of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN 2Comprehensive Wound Center, Indiana University Health, Indianapolis, IN 3Department of Surgery, Division of Vascular Surgery, Indiana University School of Medicine, Indianapolis, IN
Sunil Kumar1, Miguel Jorge1, Imran Khan1, Ethan Rinne1, Bryce Hockman1,2, Kaitlyn Depinet2, Beth Altenburger2, Jaimee Hann2, Gregory Westin2,3, Mithun Sinha1
1Department of Surgery, Division of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN 2Comprehensive Wound Center, Indiana University Health, Indianapolis, IN 3Department of Surgery, Division of Vascular Surgery, Indiana University School of Medicine, Indianapolis, IN
I.06. Shell or the Cargo? Significance of Keratinocyte-Derived Exosomes Surface Molecules In Tissue Repair
Anu Sharma1, Anita Yadav1, David Clemmer2, Sashwati Roy1, Chandan K. Sen1, Subhadip Ghatak1
1Surgery, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, United States. 2Chemistry, Indiana University, Bloomington, Indianapolis, IN, United States
Anu Sharma1, Anita Yadav1, David Clemmer2, Sashwati Roy1, Chandan K. Sen1, Subhadip Ghatak1
1Surgery, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, United States. 2Chemistry, Indiana University, Bloomington, Indianapolis, IN, United States
I.07. Structural Equation Model To Quantify Importance Of Patient Factors And Wound Microbiome On Healing
Jacob Ancira4, Rebecca Gabrilska1, Craig Tipton4, Clint Miller2, Zachary Stickley3, Khalid Omeir4, Joseph Wolcott2, Todd D. Little3, Caleb Phillips4
1Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States. 2Southwest Regional Wound Care Center, Lubbock, TX, United States. 3Department of Educational Psychology and Leadership, Texas Tech University, Lubbock, TX, United States. 4Department of Biological Sciences, Texas Tech University, Lubbock, TX, United States
Jacob Ancira4, Rebecca Gabrilska1, Craig Tipton4, Clint Miller2, Zachary Stickley3, Khalid Omeir4, Joseph Wolcott2, Todd D. Little3, Caleb Phillips4
1Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States. 2Southwest Regional Wound Care Center, Lubbock, TX, United States. 3Department of Educational Psychology and Leadership, Texas Tech University, Lubbock, TX, United States. 4Department of Biological Sciences, Texas Tech University, Lubbock, TX, United States
I.08. The Histone Methyltransferase Whsc1 Regulates TGF?-driven Macrophage to Myofibroblast Transition During Wound Healing
Kevin Mangum1, Amrita Joshi1, Sonya Wolf1, Jadie Moon1, Andrea Obi1, Beth Moore2, Frank Davis1, Katherine Gallagher1
1Vascular Sugery, University of Michigan, Ann Arbor, MI, United States 2Department of Immunology and Microbiology, University of Michigan, Ann Arbor, MI, United States
Kevin Mangum1, Amrita Joshi1, Sonya Wolf1, Jadie Moon1, Andrea Obi1, Beth Moore2, Frank Davis1, Katherine Gallagher1
1Vascular Sugery, University of Michigan, Ann Arbor, MI, United States 2Department of Immunology and Microbiology, University of Michigan, Ann Arbor, MI, United States
I.09. ETRS: Soluble CD83 Improves Wound Healing in a 3D Wound Healing Model and Promotes Resolution of the Inflammatory Milieu In Chronic Wounds
Christian Hollard1,2, K. Peckert-Maier1, C. Erfurt-Berge2, A. Steinkasserer1, D. Royzman1
1Departent of Immune Modulation, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, 2Department of Dermatology, Universitätsklinikum Erlangen, Erlangen, Germany
Christian Hollard1,2, K. Peckert-Maier1, C. Erfurt-Berge2, A. Steinkasserer1, D. Royzman1
1Departent of Immune Modulation, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, 2Department of Dermatology, Universitätsklinikum Erlangen, Erlangen, Germany
4:00 PM - 4:15 PM
BREAK
4:15 PM - 5:15 PM
WHS SESSION J: AI Approaches in Wound Healing
Moderators: Kyle Quinn, PhD; Allan Wells, MD, DMSc
Machine learning and artificial intelligence (AI) approaches are being increasingly used with great benefit in numerous scientific fields. A number of emerging approaches are being developed to analyze large datasets with the goal of better understanding the process of wound healing, developing better diagnostics and improving clinical care. This session will focus on new AI approaches and how they can be applied to wound healing research, diagnostics, and clinical care.
Moderators: Kyle Quinn, PhD; Allan Wells, MD, DMSc
Machine learning and artificial intelligence (AI) approaches are being increasingly used with great benefit in numerous scientific fields. A number of emerging approaches are being developed to analyze large datasets with the goal of better understanding the process of wound healing, developing better diagnostics and improving clinical care. This session will focus on new AI approaches and how they can be applied to wound healing research, diagnostics, and clinical care.
Speakers:
 |
Machine Learning Methods To Quantify Wound Stage Progression And Inform Feedback Control Strategies To Accelerate Wound Closure Marcella Gomez, PhD |
 |
Pressure Injuries: What Have We Learned and How Can This Knowledge Be Used To Better Protect Patients? Amit Gefen, PhD |
5:15 PM - 7:45 PM
GRAND OPENING OF EXHIBITS/COCKTAIL RECEPTION
DAY 3: THURSDAY, MAY 16, 2024
7:00 AM - 9:00 AM
WHS Committee Meetings
9:00 AM - 9:15 AM
BREAK
9:15 AM - 10:15 AM
WHS SESSION K: Concurrent Oral Abstracts I (non-accredited)
Oral abstract presentations will feature the highest scoring abstracts submitted to the WHS.
Oral abstract presentations will feature the highest scoring abstracts submitted to the WHS.
K1: Infections/Biofilms 1
Moderators: Sasha Shafikhani & Lindsay Kalan
Moderators: Sasha Shafikhani & Lindsay Kalan
K1.01. What is Slough? Defining the proteomic and microbial composition of wound slough and its implications for wound healing
Elizabeth Townsend1, Alex Cheong1, Michael Radzietza2, Blaine Fritz3, Matthew Malone2, Thomas Bjarnsholt3, Karen Ousey4, Terry Swanson4, Gregory S. Schultz4, Angela Gibson1, Lindsay Kalan1
1University of Wisconsin, Madison, WI, United States 2Western Sydney University, Penrith, NSW, Australia. 3University of Copenhagen, Copenhagen, Denmark. 4International Wound Infection Institute, London, United Kingdom
Elizabeth Townsend1, Alex Cheong1, Michael Radzietza2, Blaine Fritz3, Matthew Malone2, Thomas Bjarnsholt3, Karen Ousey4, Terry Swanson4, Gregory S. Schultz4, Angela Gibson1, Lindsay Kalan1
1University of Wisconsin, Madison, WI, United States 2Western Sydney University, Penrith, NSW, Australia. 3University of Copenhagen, Copenhagen, Denmark. 4International Wound Infection Institute, London, United Kingdom
K1.02. Analysis Of 9,241 Wound Specimens Reveals Six Major Microbiome Community Types And Meteorological Associations
Craig Tipton1, Rebecca Gabrilska2, Jacob Ancira1, Courtney Jarvis3, Lars Koenig3, Karin Ardon-Dryer4, Kendra Rumbaugh2, Caleb Phillips1
1Biological Sciences, Texas Tech University, Lubbock, TX, United States 2Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States 3MicroGen DX, Lubbock, TX, United States 4Atmospheric Science Group, Texas Tech University, Lubbock, TX, United States
Craig Tipton1, Rebecca Gabrilska2, Jacob Ancira1, Courtney Jarvis3, Lars Koenig3, Karin Ardon-Dryer4, Kendra Rumbaugh2, Caleb Phillips1
1Biological Sciences, Texas Tech University, Lubbock, TX, United States 2Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States 3MicroGen DX, Lubbock, TX, United States 4Atmospheric Science Group, Texas Tech University, Lubbock, TX, United States
K1.03. A Disposable Device For Fast Screening Of Diabetic Foot Ulcer Infection
Jon Senkowsky2, Shuxin Li1, Wenjing Hu1, Liping Tang1
1Progenitec, Arlington, TX, United States 2Texas Health Physician’s group, Arlington, TX, United States
Jon Senkowsky2, Shuxin Li1, Wenjing Hu1, Liping Tang1
1Progenitec, Arlington, TX, United States 2Texas Health Physician’s group, Arlington, TX, United States
K1.04. Pseudomonas Aeruginosa Activates Lasi/R Quorum Sensing, Selective Antioxidant Enzymes, And Type Vi Secrection System During Biofilm Formation And Chronic Wound Initiation
Jane Kim, Brandon Le, Weifeng Gu, Manuela M. Martins-Green
University of California, Riverside, Fullerton, CA, United States
Jane Kim, Brandon Le, Weifeng Gu, Manuela M. Martins-Green
University of California, Riverside, Fullerton, CA, United States
K1.05. Detection And Photoablation Of Wound Biofilm Infections With Theranostic Gold-In-Gold Cage Nanoparticles
Maryam Hajfathalian1, Christiaan R. de Vries1, Yuxi C. Dong2, Ahmad Amirshaghaghi2, Pallavi Jonnalagadda2, Jessica HSU2, Aimen Zlitni1, David Cormode2, Paul Bollyky1
1Stanford University, Mountain View, CA, United States 2University of Pennsylvania, Philadelphia, PA, United States
Maryam Hajfathalian1, Christiaan R. de Vries1, Yuxi C. Dong2, Ahmad Amirshaghaghi2, Pallavi Jonnalagadda2, Jessica HSU2, Aimen Zlitni1, David Cormode2, Paul Bollyky1
1Stanford University, Mountain View, CA, United States 2University of Pennsylvania, Philadelphia, PA, United States
K1.06. Extracellular Granzyme B Contributes To Delayed Healing Of Cutaneous Leishmaniasis In A Murine Model
Layla Nabai1, Yasaman Kaviani1, Katlyn Richardson1, Alexandre Aubert1, Karen Jung1, Farhad Handjani2, Reza Yaghoobi3, Nicholas Carr4, Hongyan Zhao1, Robert McMaster5, David Granville1
1Pathology and laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. 2Molecular Dermatology Research Centre, Shiraz university of Medical Sciences, Shiraz, Iran (the Islamic Republic of). 3Department of Dermatology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran (the Islamic Republic of). 4Department of Surgery/Division of Plastic Surgery, University of British Columbia, Vancouver, BC, Canada. 5Faculty of Medicine, Medical Genetics, University of British Columbia, Vancouver, BC, Canada
Layla Nabai1, Yasaman Kaviani1, Katlyn Richardson1, Alexandre Aubert1, Karen Jung1, Farhad Handjani2, Reza Yaghoobi3, Nicholas Carr4, Hongyan Zhao1, Robert McMaster5, David Granville1
1Pathology and laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. 2Molecular Dermatology Research Centre, Shiraz university of Medical Sciences, Shiraz, Iran (the Islamic Republic of). 3Department of Dermatology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran (the Islamic Republic of). 4Department of Surgery/Division of Plastic Surgery, University of British Columbia, Vancouver, BC, Canada. 5Faculty of Medicine, Medical Genetics, University of British Columbia, Vancouver, BC, Canada
K2: Fibrosis/Scarring 1
Moderators: Daniel Gibson & Kellen Chen
Moderators: Daniel Gibson & Kellen Chen
K2.01. Circulating Mechanoresponsive Myeloid Cells Contribute to Fibrosis Across Disease States and Organ Systems
Kellen Chen2, Dominic Henn2, Dharshan Sivaraj2, Katharina S. Fischer2, Jagannath Padmanabhan1, Michael Januszyk1, Geoffrey C. Gurtner2
1Surgery, Stanford University, Irvine, CA, United States 2Surgery, University of Arizona, Tucson, AZ, United States
Kellen Chen2, Dominic Henn2, Dharshan Sivaraj2, Katharina S. Fischer2, Jagannath Padmanabhan1, Michael Januszyk1, Geoffrey C. Gurtner2
1Surgery, Stanford University, Irvine, CA, United States 2Surgery, University of Arizona, Tucson, AZ, United States
K2.02. Direct Contact With Mechanically Activated Myofibroblasts Drives Macrophages Into Distinct Transcriptional And Functional States
Li Diao1, Ronen Schuster2, Fereshteh Younesi1, Boris Hinz1
1LTRR, Unity Health Toronto, Toronto, ON, Canada. 2CytoReason, Tel Aviv, Israel
Li Diao1, Ronen Schuster2, Fereshteh Younesi1, Boris Hinz1
1LTRR, Unity Health Toronto, Toronto, ON, Canada. 2CytoReason, Tel Aviv, Israel
K2.03. The Role of Periostin and Hyaluronan Crosstalk in the Regulation of Wound Fibrosis
Sonya Keswani, Tanuj J. Prajapati, Hui Li, Ling Yu, Swathi Balaji
Baylor College of Medicine, Houston, TX, United States
Sonya Keswani, Tanuj J. Prajapati, Hui Li, Ling Yu, Swathi Balaji
Baylor College of Medicine, Houston, TX, United States
K2.04. Microfibril Associated Protein 5 And The Regulation Of Skin Scar Formation
Chen Han1, Heidi Yuan1, Lin Chen1, Timothy J. Koh1, Robert P. Mecham2, Luisa A. DiPietro1
1Center for Wound Healing and Tissue Regeneration, University of Illinois College of Medicine at Chicago, Chicago, IL, United States 2Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, MO, United States
Chen Han1, Heidi Yuan1, Lin Chen1, Timothy J. Koh1, Robert P. Mecham2, Luisa A. DiPietro1
1Center for Wound Healing and Tissue Regeneration, University of Illinois College of Medicine at Chicago, Chicago, IL, United States 2Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, MO, United States
K2.05. Elucidating the Role of sFRP2 in Modulating Organ Fibrosis
Delany Bradford1, Pampee Young2, Sarika Saraswati1
1Tennessee State University, Nashville, TN, United States 2American Red Cross, Nashville, TN, United States
Delany Bradford1, Pampee Young2, Sarika Saraswati1
1Tennessee State University, Nashville, TN, United States 2American Red Cross, Nashville, TN, United States
K2.06. Divergent Contributions Of Systemic Immune Cells And Local Fibroblasts To Wound Closure And Fibrosis
Andrew Hostler, William Hahn, Jenne Stensland, Katharina Fischer, Maria Gracia Mora Pinos, Jared S. Holley, Abdelrahman Alsharif, Jonathan P. Yasmeh, Fidel Saenz, Autumn Lester, Hudson C. Kussie, Eamonn McKenna, Maia Granoski, Amelia B. Knoch
Surgery, University of Arizona College of Medicine -Tucson, Tucson, AZ, United States
Andrew Hostler, William Hahn, Jenne Stensland, Katharina Fischer, Maria Gracia Mora Pinos, Jared S. Holley, Abdelrahman Alsharif, Jonathan P. Yasmeh, Fidel Saenz, Autumn Lester, Hudson C. Kussie, Eamonn McKenna, Maia Granoski, Amelia B. Knoch
Surgery, University of Arizona College of Medicine -Tucson, Tucson, AZ, United States
K3: Acute Wounds/Angiogenesis
Moderators: Swathi Balaji & Harvey Himel
Moderators: Swathi Balaji & Harvey Himel
K3.01. Single-Cell RNA-Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in the Diabetic Ischemic Wound
Kanhaiya Singh, Manishekhar Kumar, Sujit K. Mohanty, Savita Khanna, Sashwati Roy, Chandan K. Sen
McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States
Kanhaiya Singh, Manishekhar Kumar, Sujit K. Mohanty, Savita Khanna, Sashwati Roy, Chandan K. Sen
McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States
K3.02. Tissue Nanotransfection Based Endothelial-Targeted Epigenetic Gene Editing In Vivo To Rescue Diabetic Ischemic Wounds
Sumit S. Verma, Surya Gnyawali, Chandan K. Sen, Kanhaiya Singh
Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Sumit S. Verma, Surya Gnyawali, Chandan K. Sen, Kanhaiya Singh
Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States
K3.03. AMPK and Rac1 Activity Regulation Promotes Wound Healing via Induction of Actin Cable Formation
Kento Takaya1, Yuka Imbe2, Qi Wang2, Shigeki Sakai1, Keisuke Okabe1, Noriko Aramaki-Hattori1, Kazuo Kishi
1Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. 2Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan
Kento Takaya1, Yuka Imbe2, Qi Wang2, Shigeki Sakai1, Keisuke Okabe1, Noriko Aramaki-Hattori1, Kazuo Kishi
1Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. 2Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan
K3.04. A Novel Ex Vivo Human Fascio cutaneous Flap Perfusion Model to Investigate Skin Injuries
Asim Ejaz
Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, United States
Asim Ejaz
Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, United States
K3.05. Subcutaneous Injection Of Zein, A Dietary Protein, Has Positive Wound Healing Effects That Are Prevented By Fingolimod (Fty720) Treatment
Isabela Beatriz C. Nóbrega, Angélica Vitória S. Andrade, Geraldo Magela Azevedo, Claudia R. Carvalho
Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Isabela Beatriz C. Nóbrega, Angélica Vitória S. Andrade, Geraldo Magela Azevedo, Claudia R. Carvalho
Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
K3.06. Changes In The Catecholamine Adrenergic Network Support Wound Healing In Healthy Pigs
Anthony Gallegos3, Ksenia Zlobina1, Hsin-ya Yang3, Moyasar A. Alhamo3, Athena Soulika3, Mo Siadat3, Marcella Gomez1, Marco Rolandi2, Rivkah Isseroff3
1Applied Mathematics, UC Santa Cruz, Santa Cruz, CA, United States 2Electrical and Computer Engineering, UC Santa Cruz, Santa Cruz, CA, United States 3Dermatology, UC Davis, Sacramento, CA, United States
Anthony Gallegos3, Ksenia Zlobina1, Hsin-ya Yang3, Moyasar A. Alhamo3, Athena Soulika3, Mo Siadat3, Marcella Gomez1, Marco Rolandi2, Rivkah Isseroff3
1Applied Mathematics, UC Santa Cruz, Santa Cruz, CA, United States 2Electrical and Computer Engineering, UC Santa Cruz, Santa Cruz, CA, United States 3Dermatology, UC Davis, Sacramento, CA, United States
K4: Bioengineering/Biomaterials
Moderators: Mitch Sanders & Min Zhao
Moderators: Mitch Sanders & Min Zhao
K4.01. Type III Collagen Biomaterials Improve Cutaneous Wound Healing In Diabetic Mice
Daniel C. Stewart1, Yasumasa Iimori1, Becky K. Brisson1, William Yen1, David Chenoweth2, Claudia Loebel3, Jason Burdick4, Susan W. Volk1
1School of Veterinary Medicine , University of Pennsylvania, Philadelphia, PA, United States 2College of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, United States 3College of Engineering, University of Michigan, Ann Arbor, MI, United States 4College of Engineering and Applied Science, University of Colorado Boulder, Boulder, CO, United States
Daniel C. Stewart1, Yasumasa Iimori1, Becky K. Brisson1, William Yen1, David Chenoweth2, Claudia Loebel3, Jason Burdick4, Susan W. Volk1
1School of Veterinary Medicine , University of Pennsylvania, Philadelphia, PA, United States 2College of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, United States 3College of Engineering, University of Michigan, Ann Arbor, MI, United States 4College of Engineering and Applied Science, University of Colorado Boulder, Boulder, CO, United States
K4.02. Intravesicular Cytokine Profiling Of Stage Iv Pressure Ulcers Treated With NPWT vs. NPWT and Porcine Extracellular Matrix Dressing
Lauren Fang1, Richard Simman2
1University of Toledo College of Medicine, Monroe, OH, United States 2ProMedica-Jobst Vascular Institute, Toledo, OH, United States
Lauren Fang1, Richard Simman2
1University of Toledo College of Medicine, Monroe, OH, United States 2ProMedica-Jobst Vascular Institute, Toledo, OH, United States
K4.03. Laser Micropatterned Dermal Templates Improved Cultured Epithelial Autograft Handleability And Development In Vivo
Britani Blackstone1, Molly E. Baumann1, Summer Gallentine1, Dorothy Supp3, Kevin Bailey2, Heather Powell1
1Materials Science and Engineering, The Ohio State University, Columbus, OH, United States 2Surgery, Wake Forest University, Winston Salem, NC, United States 3Dermatology, University of Cincinnati, Cincinnati, OH, United States
Britani Blackstone1, Molly E. Baumann1, Summer Gallentine1, Dorothy Supp3, Kevin Bailey2, Heather Powell1
1Materials Science and Engineering, The Ohio State University, Columbus, OH, United States 2Surgery, Wake Forest University, Winston Salem, NC, United States 3Dermatology, University of Cincinnati, Cincinnati, OH, United States
K4.04. Sustained Oxygenation And Ros-Scavenging By Lignin Composites Promote Diabetic Wound Healing
Tanuj J. Prajapati1, Lane Yutzy2, Oluyinka Olutoye1, Benjamin Padon1, Walker D. Short1, Fayiz Faruk1, Sonya S. Keswani1, Nabila N. Anika1, Olivia Jung2, Phillip Kogan1, Ling Yu1, Hui Li1, Jangwook Jung2, Swathi Balaji1
1Pediactric Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX, United States 2Department Of Biological Engineering, Louisiana State University, Baton Rouge, LA, United States
Tanuj J. Prajapati1, Lane Yutzy2, Oluyinka Olutoye1, Benjamin Padon1, Walker D. Short1, Fayiz Faruk1, Sonya S. Keswani1, Nabila N. Anika1, Olivia Jung2, Phillip Kogan1, Ling Yu1, Hui Li1, Jangwook Jung2, Swathi Balaji1
1Pediactric Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX, United States 2Department Of Biological Engineering, Louisiana State University, Baton Rouge, LA, United States
K4.05. In-Situ Bioprinting With Pro-Reparative Bioinks Improves Impaired Diabetic Wound Healing
Eleftheria Angeliki Valsami1, Seol-Ha Jeong2, zhuqing li1, Enya Wang1, Jihyun Kim2, Lance Fiondella3, Su Ryon Shin2, Aristidis Veves1, Georgios Theocharidis1
1Beth Israel Deaconess Medical Center, Boston, MA, United States 2Brigham and Women’s Hospital, Boston, MA, United States 3Electrical and Computer Engineering, University of Massachusetts- Dartmouth, Boston, MA, United States
Eleftheria Angeliki Valsami1, Seol-Ha Jeong2, zhuqing li1, Enya Wang1, Jihyun Kim2, Lance Fiondella3, Su Ryon Shin2, Aristidis Veves1, Georgios Theocharidis1
1Beth Israel Deaconess Medical Center, Boston, MA, United States 2Brigham and Women’s Hospital, Boston, MA, United States 3Electrical and Computer Engineering, University of Massachusetts- Dartmouth, Boston, MA, United States
K4.06. Biodegradable Magnesium Wires Promote Neovascularization And Neuronal Growth For Wound Regeneration
Nabila N. Anika1, Ajeet Nagi1, Sonya S. Keswani1, Pranav Bommekal1, Ling Yu1, Sarah Pixley2, Swathi Balaji1
1Pediatric Surgery, Baylor College of Medicine, Houston, TX, United States 2Dept. of Pharmacology & Systems Physiology, University of Cincinnati Medical Center, Cincinnati, OH, United States
Nabila N. Anika1, Ajeet Nagi1, Sonya S. Keswani1, Pranav Bommekal1, Ling Yu1, Sarah Pixley2, Swathi Balaji1
1Pediatric Surgery, Baylor College of Medicine, Houston, TX, United States 2Dept. of Pharmacology & Systems Physiology, University of Cincinnati Medical Center, Cincinnati, OH, United States
10:15 AM - 10:30 AM
BREAK
10:30 AM - 11:30 AM
WHS SESSION L: Concurrent Oral Abstracts II (non-accredited)
Oral abstract presentations will feature the highest scoring abstracts submitted to the WHS.
Oral abstract presentations will feature the highest scoring abstracts submitted to the WHS.
L1: Chronic Wounds 1
Moderators: Kyle Quinn & Rivka Stone
Moderators: Kyle Quinn & Rivka Stone
L1.01. What Makes A Wound Become Chronic: Cellular And Molecular Processes That Lead To Chronic Wound Initiation
Parnian Jabbari1, Jane Kim1, Wei Zhang2, Brandon Le2, Manuela M. Martins-Green1
1Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, United States 2Institute for Integrative Genome Biology, Department of Botany and Plant Sciences. College of Natural and Agricultural Sciences, University of California, Riverside, Riverside, CA, United States
Parnian Jabbari1, Jane Kim1, Wei Zhang2, Brandon Le2, Manuela M. Martins-Green1
1Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, United States 2Institute for Integrative Genome Biology, Department of Botany and Plant Sciences. College of Natural and Agricultural Sciences, University of California, Riverside, Riverside, CA, United States
L1.02. Quantifying The Interaction Between Age And Diabetes On Skin Wound Metabolism Using In Vivo Multiphoton Microscopy
Marcos R. Rodriguez1, Kyle Quinn2, Malavika Nidhi1, Divya M. Gollapalli1
1Biomedical Engineering, University of Arkansas, Fayetteville, AR, United States 2Arkansas Integrative Metabolic Research Center, University of Arkansas, Fayetteville, AR, United States
Marcos R. Rodriguez1, Kyle Quinn2, Malavika Nidhi1, Divya M. Gollapalli1
1Biomedical Engineering, University of Arkansas, Fayetteville, AR, United States 2Arkansas Integrative Metabolic Research Center, University of Arkansas, Fayetteville, AR, United States
L1.03. Pten Is A Master Regulator Of Non-Healing Phenotype In Venous Leg Ulcers
Jelena Marjanovic1, Jamie L. Burgess1, Ivan Jozic1, Beatriz Abdo Abujamra1, Robert S. Kirsner1, Hadar Lev-Tov1, Harold Brem2, Momoh Ojirese2, Irena Pastar1, Marjana Tomic-Canic1
1Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States 2Rutgers New Jersey Medical School, Newark, NJ, United States
Jelena Marjanovic1, Jamie L. Burgess1, Ivan Jozic1, Beatriz Abdo Abujamra1, Robert S. Kirsner1, Hadar Lev-Tov1, Harold Brem2, Momoh Ojirese2, Irena Pastar1, Marjana Tomic-Canic1
1Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States 2Rutgers New Jersey Medical School, Newark, NJ, United States
L1.04. Transcriptional Analysis of Fibroblasts in Diabetic Wound Healing
Abdelrahman Alsharif, Katharina S. Fischer, Filiberto Quintero, Mansi Singh, Amelia B. Knochel, Ben Litmanovich, Sultana M. Mojadidi, Javier Gonzalez, Dharshan Sivaraj, Hudson C. Kussie, William Hahn, Andrew Hostler, Maia Granoski, Geoffrey C Gurtner, Kellen Chen
Department of Surgery , University of Arizona, Tucson, AZ, United States
Abdelrahman Alsharif, Katharina S. Fischer, Filiberto Quintero, Mansi Singh, Amelia B. Knochel, Ben Litmanovich, Sultana M. Mojadidi, Javier Gonzalez, Dharshan Sivaraj, Hudson C. Kussie, William Hahn, Andrew Hostler, Maia Granoski, Geoffrey C Gurtner, Kellen Chen
Department of Surgery , University of Arizona, Tucson, AZ, United States
L1.05. Vlu Wound Bed Preperation Is Highly Correlated With Wound Closure - Results From The Chronex Multicenter Rct
Marissa Carter1, Robert Snyder3, Keren David2, Yael Katz-Levy2, Ety Klinger2, Ofra Barnett-Griness4, Chaviva Peretz-Rozenblum4, John Lantis5
1Strategic Solutions, Inc., Bozeman, MT, United States 2MediWound Ltd, Yavne, Israel. 3Barry University, Miami, FL, United States 4Bioforum Ltd, Ness-Ziona, Israel. 5Mount Sinai West, Icahn School of Medicine, New York, NY, United States
Marissa Carter1, Robert Snyder3, Keren David2, Yael Katz-Levy2, Ety Klinger2, Ofra Barnett-Griness4, Chaviva Peretz-Rozenblum4, John Lantis5
1Strategic Solutions, Inc., Bozeman, MT, United States 2MediWound Ltd, Yavne, Israel. 3Barry University, Miami, FL, United States 4Bioforum Ltd, Ness-Ziona, Israel. 5Mount Sinai West, Icahn School of Medicine, New York, NY, United States
L1.06. Spinal Cord Injury And Postoperative Complications In Pressure Ulcer Closure
Namrata V. Chintalapati, Robert Galiano
Plastic Surgery, Northwestern University, Chicago, IL, United States
Namrata V. Chintalapati, Robert Galiano
Plastic Surgery, Northwestern University, Chicago, IL, United States
L2: Novel Therapies
Moderators: Daria Narmoneva & Nandini Ghosh
Moderators: Daria Narmoneva & Nandini Ghosh
L2.01. Deep Vein Thrombosis Affects Healing Outcomes In Patients With Pyoderma Gangrenosum: A Single-Center Prospective Case-Control Study
Hannah Zhao, Sidharth Sengupta, Jonathan Sisley, Olivia M. Haddadin, Alex Ortega-Loayza
OHSU, Lake Oswego, OR, United States
Hannah Zhao, Sidharth Sengupta, Jonathan Sisley, Olivia M. Haddadin, Alex Ortega-Loayza
OHSU, Lake Oswego, OR, United States
L2.02. Selective Agonism Of Histamine Receptors Augments Tissue Repair
Jordan R. Yaron, Shubham Pallod, Nicole Grigaitis, Samantha Rhodes, Dirghau M. Patel, Deepanjan Ghosh, Kaushal Rege
Biodesign Center for Biomaterials Innovation and Translation, Arizona State University, Tempe, AZ, United States
Jordan R. Yaron, Shubham Pallod, Nicole Grigaitis, Samantha Rhodes, Dirghau M. Patel, Deepanjan Ghosh, Kaushal Rege
Biodesign Center for Biomaterials Innovation and Translation, Arizona State University, Tempe, AZ, United States
L2.03. Preclinical And Clinical Development Of Sli-F06, A Novel Dermal Fibroblast Modulating Drug, In Cutaneous Wound Healing
Zhong Zheng1, Pin Ha2, Elisabeth Leeflang1, Zhaohan Zeng1, Joshua Yang2, Alyssa Miao2, Robert Galiano3, Paul Glat4, Donald Buck6, John Felder6, Kang Ting5, Chia Soo2
1Scarless Laboratories Inc., Cherry Hill, NJ, United States 2University of California, Los Angeles, Los Angeles, CA, United States 3Northwestern University, Chicago, IL, United States 4Dr. Paul Glat Clinic, Bala Cynwyd, PA, United States 5American Dental Association Forsyth Institute, Cambridge, MA, United States 6Washington University, St. Louis, MO, United States
Zhong Zheng1, Pin Ha2, Elisabeth Leeflang1, Zhaohan Zeng1, Joshua Yang2, Alyssa Miao2, Robert Galiano3, Paul Glat4, Donald Buck6, John Felder6, Kang Ting5, Chia Soo2
1Scarless Laboratories Inc., Cherry Hill, NJ, United States 2University of California, Los Angeles, Los Angeles, CA, United States 3Northwestern University, Chicago, IL, United States 4Dr. Paul Glat Clinic, Bala Cynwyd, PA, United States 5American Dental Association Forsyth Institute, Cambridge, MA, United States 6Washington University, St. Louis, MO, United States
L2.04. Prophylactic, One Time Dose Of Rac Inhibitor Mitigates Foreign Body Response Through Immunomodulation At Both Early And Late Time Points
Hudson C. Kussie, Jonathan P. Yasmeh, Dharshan Sivaraj, Katharina S. Fischer, Eamonn McKenna, Brodi Stevens, Gabriel Starling, Maia Granoski, Andrew Hostler, Maisam Jafri, Geoffrey C. Gurtner, Kellen Chen
University of Arizona, Tucson, AZ
Hudson C. Kussie, Jonathan P. Yasmeh, Dharshan Sivaraj, Katharina S. Fischer, Eamonn McKenna, Brodi Stevens, Gabriel Starling, Maia Granoski, Andrew Hostler, Maisam Jafri, Geoffrey C. Gurtner, Kellen Chen
University of Arizona, Tucson, AZ
L2.05. Comparison Of Bromelain-Based Enzymatic Debridement To Collagenase Satyl® Ointment - Analyses From The Chronex Multicenter Rct
Dove Cyaandi1, Robert Snyder2, Keren David3, Yael Katz-Levy3, Ety Klinger3, Felix Sigal4
1University Health, San Antonio, TX, United States 2Barry University, Miami, FL, United States 3MediWound Ltd, Yavne, Israel. 4Angel City Research, Los Angeles, CA, United States
Dove Cyaandi1, Robert Snyder2, Keren David3, Yael Katz-Levy3, Ety Klinger3, Felix Sigal4
1University Health, San Antonio, TX, United States 2Barry University, Miami, FL, United States 3MediWound Ltd, Yavne, Israel. 4Angel City Research, Los Angeles, CA, United States
L2.06. A Longitudinal Single-Cell Transcriptomic Atlas Of Diabetic Porcine Wounds Reveals Distinct Fibroblast Subtypes And Trajectories In Response To Tissue Mechanical Manipulation
Ming Guan1, Nikolaos Kalavros2, Zhuqing Li1, Enya Wang1, Mauricio Contreras1, Jingjing Wu3, Xuanhe Zhao3, Ioannis Vlachos2, Georgios Theocharidis1, Aristidis Veves1
1Joslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu, MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States 2Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States 3Department of Mechanical Engineering, Massachusetts Institute of Technology, Boston, MA, United States
Ming Guan1, Nikolaos Kalavros2, Zhuqing Li1, Enya Wang1, Mauricio Contreras1, Jingjing Wu3, Xuanhe Zhao3, Ioannis Vlachos2, Georgios Theocharidis1, Aristidis Veves1
1Joslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu, MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States 2Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States 3Department of Mechanical Engineering, Massachusetts Institute of Technology, Boston, MA, United States
L3: Biological Dressings and Matrices
Moderators: Kanhaiya Singh & Kara Spiller
Moderators: Kanhaiya Singh & Kara Spiller
L3.01. Resolution of Bioburden and Wound Closure in a Porcine Full Thickness Wound Model
Justin Avery1, Joel Gil2, Kelly Kimmerling1, Stephen Davis2, Katie Mowry1
1Research & Development, Organogenesis, Birmingham, AL, United States 2Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL, United States
Justin Avery1, Joel Gil2, Kelly Kimmerling1, Stephen Davis2, Katie Mowry1
1Research & Development, Organogenesis, Birmingham, AL, United States 2Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL, United States
L3.02. Efficacy and Safety Of Dressing Containing Novel Antimicrobial Peptide For Managing Wound Biofilm
Jennifer Neff1*, John C. Vitucci2,3, Ryan Cummings1, Danir Bayramov1, Ashley Miller2,3, Jonathan Benaye2,4, Abigail Livingston2,4, John A. Cleary2,4, Jesse Smith2,3, Rhonda Lizewski2, Noah Gold2,4, Katy Garcia2,4, Yoann Le Breton2, Frederic Poly2, Alexandria Kesterson2
1Allvivo Vascular, Inc., Lake Forest, CA. 2 Naval Medical Research Command (NMRC), Silver Spring, MD. 3The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, MD. 4 General Dynamics Information Technology (GDIT), Reston, VA.
Jennifer Neff1*, John C. Vitucci2,3, Ryan Cummings1, Danir Bayramov1, Ashley Miller2,3, Jonathan Benaye2,4, Abigail Livingston2,4, John A. Cleary2,4, Jesse Smith2,3, Rhonda Lizewski2, Noah Gold2,4, Katy Garcia2,4, Yoann Le Breton2, Frederic Poly2, Alexandria Kesterson2
1Allvivo Vascular, Inc., Lake Forest, CA. 2 Naval Medical Research Command (NMRC), Silver Spring, MD. 3The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, MD. 4 General Dynamics Information Technology (GDIT), Reston, VA.
L3.03. Novel Antibiotic-Free Biomimetic Wound Matrix Provides Antimicrobial Protection And Superior Healing
Brunno F. Caetano, Trudy-Ann Grant, Bishnu P. Joshi, Adam Finzen, Tarak Bhakda, Rebecca Salamone, Manav Mehta, Ana Tellechea
Gel4Med Inc., Lowell, MA, United States
Brunno F. Caetano, Trudy-Ann Grant, Bishnu P. Joshi, Adam Finzen, Tarak Bhakda, Rebecca Salamone, Manav Mehta, Ana Tellechea
Gel4Med Inc., Lowell, MA, United States
L3.04. Treating Diabetic Fibroblasts Through Tunable Hyalurononan-Binding Silk Fibroin Therapeutic Hydrogels
Amelia Huffer, Tugba Ozdemir
Nanoscience and Biomedical Engineering, South Dakota School of Mines and Technology, Rapid City, SD, United States
Amelia Huffer, Tugba Ozdemir
Nanoscience and Biomedical Engineering, South Dakota School of Mines and Technology, Rapid City, SD, United States
L3.05. Finite Element Analysis, Preclinical, And Proteomic Assessment Of A Novel 7-Day Extended Wear Peel And Place Negative Pressure Wound Therapy Dressing
Diwi Allen1, Samantha A. Mann1, Balakrishna Haridas2, Brenda Marchand1, Marisa Schmidt1, Kris Kieswetter1
1Medical Solutions Division, 3M Company, San Antonio, TX, United States 2Device & Implant Innovations, College Station, TX, United States
Diwi Allen1, Samantha A. Mann1, Balakrishna Haridas2, Brenda Marchand1, Marisa Schmidt1, Kris Kieswetter1
1Medical Solutions Division, 3M Company, San Antonio, TX, United States 2Device & Implant Innovations, College Station, TX, United States
L3.06. Wound Histology Through Virtual Staining Using Generative Adversarial Networks
Malavika Nidhi, Jake Jones, Alan Woessner, Kyle Quinn
Biomedical Engineering, University of Arkansas, Fayetteville, AR, United States
Malavika Nidhi, Jake Jones, Alan Woessner, Kyle Quinn
Biomedical Engineering, University of Arkansas, Fayetteville, AR, United States
L4: Clinical Indicators
Moderators: Adrian Barbul & John Gwin
Moderators: Adrian Barbul & John Gwin
L4.01. Easing The Pressure In Wound Therapy: Evaluating Chatgpt’s Management And Treatment Of Wounds
Daniel Najafali1, Timothy W. King2
1Plastic and Reconstructive Surgery, Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, IL, USA, Urbana, IL, United States 2Plastic and Reconstructive Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, United States
Daniel Najafali1, Timothy W. King2
1Plastic and Reconstructive Surgery, Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, IL, USA, Urbana, IL, United States 2Plastic and Reconstructive Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, United States
L4.02. DNA Methylation Profiling for the Prediction of Recurrences and Prognosis in Patients with Diabetic Foot Ulcers
Sik Namgoong
Plastic Surgery, Stanford University, Irvine, CA, United States
Sik Namgoong
Plastic Surgery, Stanford University, Irvine, CA, United States
L4.03. Racial Disparities In Incidence Of And Access To Hypertrophic And Keloid Scar Management
Krish V. Shah1, Stuti P. Garg2, Robert D. Galiano2
1Case Western Reserve University School of Medicine, Cleveland, OH, United States 2Northwestern University Feinberg School of Medicine, Chicago, IL, United States
Krish V. Shah1, Stuti P. Garg2, Robert D. Galiano2
1Case Western Reserve University School of Medicine, Cleveland, OH, United States 2Northwestern University Feinberg School of Medicine, Chicago, IL, United States
L4.04. Evaluating TEWL as a Predicitve Marker for Reulceration in Healed Chronic Diabetic Foot Ulcers
Rawlings E. Lyle1, Pallas Lim2, Mirabel Dafinone2, Sara Dahle3, Rivkah Isseroff4
1School of Medicine, University of California, Davis, Sacramento, CA, United States 2Dermatology Section, VA Northern California Health Care System, Mather, CA, United States 3Podiatry Section, VA Northern California Health Care System, Mather, CA, United States 4Department of Dermatology, University of California, Davis, Sacramento, CA, United States
Rawlings E. Lyle1, Pallas Lim2, Mirabel Dafinone2, Sara Dahle3, Rivkah Isseroff4
1School of Medicine, University of California, Davis, Sacramento, CA, United States 2Dermatology Section, VA Northern California Health Care System, Mather, CA, United States 3Podiatry Section, VA Northern California Health Care System, Mather, CA, United States 4Department of Dermatology, University of California, Davis, Sacramento, CA, United States
L4.05. Discarded Wound Dressings: An Untapped Source Of Predictive And Monitoring Biomarkers Of Multiple Types Of Wounds
Victoria Soto1, Sujad Younis2, Natasa Strbo2, Matthew Hardy3, Jason Levine4, Monica Perez4, Juan O. Bravo1, Hadar Lev-Tov1, Robert S. Kirsner1, Ivan Jozic1
1Dermatology, University of Miami School of Medicine, Miami, FL, United States 2Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States 3Miami VA Medical Center, Miami, FL, United States 4Division of Endocrinology, Metabolism and Diabetes, University of Miami Miller School of Medicine, Miami, FL, United States
Victoria Soto1, Sujad Younis2, Natasa Strbo2, Matthew Hardy3, Jason Levine4, Monica Perez4, Juan O. Bravo1, Hadar Lev-Tov1, Robert S. Kirsner1, Ivan Jozic1
1Dermatology, University of Miami School of Medicine, Miami, FL, United States 2Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States 3Miami VA Medical Center, Miami, FL, United States 4Division of Endocrinology, Metabolism and Diabetes, University of Miami Miller School of Medicine, Miami, FL, United States
L4.06. Detection of Predictive Human Genetic Markers Of The Wound Microbiome
Rebecca Gabrilska1, Khalid Omeir2, Ashley Noe2, Jacob Ancira2, Clint Miller3, Craig Tipton2, Kendra Rumbaugh1, Joseph Wolcott3, Nicole Phillips4, Caleb Phillips2
1Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States 2Biological Sciences, Texas Tech University, Lubbock, TX, United States 3Southwest Regional Wound Care Center, Lubbock, TX, United States 4Microbiology, Immunology & Genetics, University of North Texas Health Sciences Center, Fort Worth, TX, United States
Rebecca Gabrilska1, Khalid Omeir2, Ashley Noe2, Jacob Ancira2, Clint Miller3, Craig Tipton2, Kendra Rumbaugh1, Joseph Wolcott3, Nicole Phillips4, Caleb Phillips2
1Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States 2Biological Sciences, Texas Tech University, Lubbock, TX, United States 3Southwest Regional Wound Care Center, Lubbock, TX, United States 4Microbiology, Immunology & Genetics, University of North Texas Health Sciences Center, Fort Worth, TX, United States
11:30 AM - 2:00 PM
LUNCH WITH EXHIBITORS
12:15 PM - 2:00 PM
WHS MEET THE MENTORS (non-accredited)
Taking a Research Idea from the Bench to the Clinic
Moderator: Rivkah Isseroff, MD
Speakers: Geoffrey C. Gurtner, MD;
Gautam Ghatnekar
Taking a Research Idea from the Bench to the Clinic
Moderator: Rivkah Isseroff, MD
Speakers: Geoffrey C. Gurtner, MD;
Gautam Ghatnekar
2:00 PM - 2:15 PM
BREAK
2:15 PM - 3:15 PM
WHS SESSION M: Tissue Engineering and Biomaterials
Moderators: Daria Narmoneva, PhD; Heather Powell, PhD
The fields of tissue engineering and biomaterials research are advancing at a rapid pace. A number of novel tissue-engineered substrates and biomaterials with pro-healing properties are being generated and tested. Interactions between these engineered materials and cells are important to the healing process. This session will highlight newly developed approaches to enhance engineered tissues and biomaterials with the capacity to improve wound healing.
Moderators: Daria Narmoneva, PhD; Heather Powell, PhD
The fields of tissue engineering and biomaterials research are advancing at a rapid pace. A number of novel tissue-engineered substrates and biomaterials with pro-healing properties are being generated and tested. Interactions between these engineered materials and cells are important to the healing process. This session will highlight newly developed approaches to enhance engineered tissues and biomaterials with the capacity to improve wound healing.
Speakers:
 |
Using Nature's Blueprint to Design Biodegradable Biomaterials Enhancing Soft Tissue Healing Willeke Daamen, PhD |
 |
Advances in Particulate-Based Immunotherapy Of Autoinflammatory Diseases Jamal Lewis, PhD |
3:15 PM - 3:30 PM
BREAK
3:30 PM - 4:30 PM
WHS SESSION N: Awardee Spotlight
Moderators: Traci Wilgus, PhD; Timothy Koh, PhD
This session will highlight the work of individuals that have recently received awards for their work, including the WHS Lifetime Achievement Award winner and several junior faculty members that have been recipients of research-related awards.
Moderators: Traci Wilgus, PhD; Timothy Koh, PhD
This session will highlight the work of individuals that have recently received awards for their work, including the WHS Lifetime Achievement Award winner and several junior faculty members that have been recipients of research-related awards.
Speakers:
 |
A Wound Surgeon's Journey of Hope and Resilience Lisa Gould, MD, PhD |
 |
Development of Repurposed-Drug-Releasing-Dressings for Treatment of Diabetic Wounds Georgios Theocharidis, PhD |
 |
Physiological Modulation of Mesenchymal Stem/Stromal Cell Secretome for Skin Wound Healing Helena Zomer, DVM, PhD |
4:30 PM - 4:45 PM
BREAK
4:45 PM - 5:45 PM
WHS DAY 3 GENERAL SESSION
Moderators: Timothy Koh, PhD; Swathi Balaji, PhD
The process of wound healing is enormously complex, as it involves numerous cell types, mediators, and extracellular matrix molecules. Thousands of molecules are produced in response to injury, and many hundreds of these have been shown to play a functional role in tissue repair. The complexity of healing creates many questions about how cells communicate in the wound and about how genes are regulated following injury. Advances in technology and computational approaches now allow the identification of unique wound communication pathways and gene networks. These discoveries may lead to improved strategies to guide tissue regeneration.
Moderators: Timothy Koh, PhD; Swathi Balaji, PhD
The process of wound healing is enormously complex, as it involves numerous cell types, mediators, and extracellular matrix molecules. Thousands of molecules are produced in response to injury, and many hundreds of these have been shown to play a functional role in tissue repair. The complexity of healing creates many questions about how cells communicate in the wound and about how genes are regulated following injury. Advances in technology and computational approaches now allow the identification of unique wound communication pathways and gene networks. These discoveries may lead to improved strategies to guide tissue regeneration.
Speakers:
 |
Talking About Wounds: Communication Pathways Within A Complex Process Luisa Ann DiPietro, DDS, PhD |
5:45 PM - 6:00 PM
BREAK
6:00 PM - 6:30 PM
WHS SESSION O: Rapid Fire Poster Presentations (non-accredited)
Moderators: Rivka Stone, MD, PhD; Subhadip Ghatak, PhD
This session will highlight the highest scoring abstracts selected for poster presentations. Eight short 'rapid-fire' poster talks will be featured. Presenters will have one slide and two minutes to summarize novel research findings, then one minute to answer questions. All poster presenters will be available at the poster gala to discuss their research.
Moderators: Rivka Stone, MD, PhD; Subhadip Ghatak, PhD
This session will highlight the highest scoring abstracts selected for poster presentations. Eight short 'rapid-fire' poster talks will be featured. Presenters will have one slide and two minutes to summarize novel research findings, then one minute to answer questions. All poster presenters will be available at the poster gala to discuss their research.
O1.01. Impact of Extracellular Matrix Graft Composition on Degradation Dynamics and Scaffold Functionality
Katrina Harmon, Miranda Burnette, Justin Avery, Kelly Kimmerling, Katie Mowry
Research & Development, Organogenesis, Birmingham, AL, United States
Katrina Harmon, Miranda Burnette, Justin Avery, Kelly Kimmerling, Katie Mowry
Research & Development, Organogenesis, Birmingham, AL, United States
O1.02. The Balance Between Cell Contractility And Adhesion Modulates Provisional Matrix Assembly During Wound Closure
Emily Davis, Marina Uroz, Christopher Chen, Jeroen Eyckmans
Biomedical Engineering, Boston University, Brookline, MA, United States
Emily Davis, Marina Uroz, Christopher Chen, Jeroen Eyckmans
Biomedical Engineering, Boston University, Brookline, MA, United States
O1.03. Mechano-Immuno-Fibrotic Wound Healing Pathways Regulate The Cellular And Molecular Ecology Of Foreign Body Response
Andrew Hostler, William Hahn, Jenne Stensland, Katharina Fischer, Abdelrahman Alsharif, Maria Gracia Mora Pinos, Hudson C. Kussie, Autumn Lester, Fidel Saenz, Jonathan P. Yasmeh, Eamonn McKenna, maisam Jafri1, Maia Granoski, Jose Vasquez, Amelia B. Knochel, Aaron Mason, Kellen Chen, Geoffrey C. Gurtner
Surgery, University of Arizona College of Medicine -Tucson, Tucson, AZ, United States
Andrew Hostler, William Hahn, Jenne Stensland, Katharina Fischer, Abdelrahman Alsharif, Maria Gracia Mora Pinos, Hudson C. Kussie, Autumn Lester, Fidel Saenz, Jonathan P. Yasmeh, Eamonn McKenna, maisam Jafri1, Maia Granoski, Jose Vasquez, Amelia B. Knochel, Aaron Mason, Kellen Chen, Geoffrey C. Gurtner
Surgery, University of Arizona College of Medicine -Tucson, Tucson, AZ, United States
O1.04. Senescent-Associated Extracellular Matrix Production And Delayed Wound Healing By Senescent Dermal Fibroblasts
Anish Srinivas Vasan1, Emma Lejeune1, Wilson Wong1, Daniel S. Roh2, Christopher Chen1, Jeroen Eyckmans1
1Biomedical Engineering, Boston University, Boston, MA, United States 2School of Medicine, Boston University, Boston, MA, United States
Anish Srinivas Vasan1, Emma Lejeune1, Wilson Wong1, Daniel S. Roh2, Christopher Chen1, Jeroen Eyckmans1
1Biomedical Engineering, Boston University, Boston, MA, United States 2School of Medicine, Boston University, Boston, MA, United States
O1.05. Lineage Tracing Of Vasculogenic Fibroblasts In Vivo and Their Significance In The Rescue Of Diabetic Ischemic Tissue
Kanhaiya Singh1, Sedat Kacar2, Sumit S. Verma1, Manishekhar Kumar1, Sashwati Roy1, Chandan K. Sen1
1McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States 2Indiana University, Indianapolis, IN, United States
Kanhaiya Singh1, Sedat Kacar2, Sumit S. Verma1, Manishekhar Kumar1, Sashwati Roy1, Chandan K. Sen1
1McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States 2Indiana University, Indianapolis, IN, United States
O1.06. Wound Alkalinity Measurement To Prognosticate The Healing Activities of DFUs
Jon Senkowsky2, Shuxin Li1, Wenjing Hu1, Liping Tang1
1Progenitec, Arlington, TX, United States 2Texas Health Physician’s group, Arlington, TX, United States
Jon Senkowsky2, Shuxin Li1, Wenjing Hu1, Liping Tang1
1Progenitec, Arlington, TX, United States 2Texas Health Physician’s group, Arlington, TX, United States
O1.07. Anthocyanins From Black Soybean Seed Coat Prevent Radiation-Induced Skin Fibrosis By Downregulating Tgf-? And Smad3 Expression
Jaehoon Choi
Department of plastic and reconstructive surgery, Keimyung University School of Medicine, Daegu, Daegu, Korea (the Republic of)
Jaehoon Choi
Department of plastic and reconstructive surgery, Keimyung University School of Medicine, Daegu, Daegu, Korea (the Republic of)
O1.08. Granzyme B Mediates Degradation Of Hemidesmosome Proteins In Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Michael M. Lane1, Faith Liu1, Alexandre Aubert1, Valerio Russo1, Karen Jung1, Touraj Khosravi2, Hongyan Zhao1, Layla Nabai1, Richard Crawford2, Elizabeth Phillips3, David Granville1
1Pathology and Laboratory Medicine, The University of British Columbia, Port Coquitlam, BC, Canada. 2Dermatology and Skin Science, The University of British Columbia, Vancouver, BC, Canada. 3Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, United States
Michael M. Lane1, Faith Liu1, Alexandre Aubert1, Valerio Russo1, Karen Jung1, Touraj Khosravi2, Hongyan Zhao1, Layla Nabai1, Richard Crawford2, Elizabeth Phillips3, David Granville1
1Pathology and Laboratory Medicine, The University of British Columbia, Port Coquitlam, BC, Canada. 2Dermatology and Skin Science, The University of British Columbia, Vancouver, BC, Canada. 3Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, United States
6:30 PM - 7:00 PM
WHS BUSINESS MEETING
7:00 PM - 7:15 PM
WHS AWARD SESSION
7:00 PM - 8:30 PM
WHS AND SAWC SPRING POSTER GALA/AWARDS
DAY 4: FRIDAY, MAY 17, 2024
9:15 AM - 10:15 AM
WHS DAY 4 GENERAL SESSION
Moderators: Rivkah Isseroff, MD; Marjana Tomic-Canic, PhD
Dr. Martin is a Professor of Cell Biology at the University of Bristol. His research focuses on understanding the genetics and cell biology of wound healing using a variety of model organisms, including fruit flies, zebrafish, and mice. The overall goal of this work is to uncover basic mechanisms of wound healing that will ultimately enable the development of wound healing therapeutics for patients. His laboratory uses cutting-edge techniques to understand what regulates the processes of reepithelialization and wound inflammation, in the hope that this information might be used to generate therapies capable of accelerating healing and reducing fibrosis.
Moderators: Rivkah Isseroff, MD; Marjana Tomic-Canic, PhD
Dr. Martin is a Professor of Cell Biology at the University of Bristol. His research focuses on understanding the genetics and cell biology of wound healing using a variety of model organisms, including fruit flies, zebrafish, and mice. The overall goal of this work is to uncover basic mechanisms of wound healing that will ultimately enable the development of wound healing therapeutics for patients. His laboratory uses cutting-edge techniques to understand what regulates the processes of reepithelialization and wound inflammation, in the hope that this information might be used to generate therapies capable of accelerating healing and reducing fibrosis.
Speakers:
 |
Live Imaging Wound Healing In Fish And Flies And Mice Paul Martin, BSc, PhD |
10:15 AM - 10:30 AM
BREAK
10:30 AM - 11:30 AM
WHS SESSION P: Concurrent Oral Abstracts III (non-accredited)
Oral presentations will feature the highest scoring abstracts submitted to the WHS.
Oral presentations will feature the highest scoring abstracts submitted to the WHS.
P1: Chronic Wounds 2
Moderators: Jamie Lee Burgess & Ivan Jozic
Moderators: Jamie Lee Burgess & Ivan Jozic
P1.01. SLI-F06, A Fibromodulin-Based Therapeutic Peptide, Enhances Wound Healing In Diabetic Rodent And Pig Models
Pin Ha2, Zhaohan Zeng1, Chenshuang Li3, Joshua Yang2, Evan Yen4, Eric Yen4, Sang Yub Kim2, Elisabeth Leeflang1, Andrew Vardanian2, Kang Ting5, Chia Soo2, ZHONG ZHENG1
1Scarless Laboratories Inc., Cherry Hill, NJ, United States 2University of California, Los Angeles, Los Angeles, CA, United States 3University of Pennsylvania, Philadelphia, PA, United States 4Arcadia High School, Arcadia, CA, United States 5American Dental Association Forsyth Institute, Cambridge, MA, United States
Pin Ha2, Zhaohan Zeng1, Chenshuang Li3, Joshua Yang2, Evan Yen4, Eric Yen4, Sang Yub Kim2, Elisabeth Leeflang1, Andrew Vardanian2, Kang Ting5, Chia Soo2, ZHONG ZHENG1
1Scarless Laboratories Inc., Cherry Hill, NJ, United States 2University of California, Los Angeles, Los Angeles, CA, United States 3University of Pennsylvania, Philadelphia, PA, United States 4Arcadia High School, Arcadia, CA, United States 5American Dental Association Forsyth Institute, Cambridge, MA, United States
P1.02. Linking Human Genetics And Wound Infection With Transcriptome-Wide Associations
Khalid Omeir1, Rebecca Gabrilska2, Jacob Ancira1, Ashley Noe1, Clint Miller3, Craig Tipton1, Kendra Rumbaugh2, Joseph Wolcott3, Nicole Phillips4, Caleb Phillips1
1Biological Sciences, Texas Tech University, Lubbock, TX, United States 2Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States 3Southwest Regional Wound Care Center, Lubbock, TX, United States 4Microbiology, Immunology & Genetics, University of North Texas Health Science Center, Fort Worth, TX, United States
Khalid Omeir1, Rebecca Gabrilska2, Jacob Ancira1, Ashley Noe1, Clint Miller3, Craig Tipton1, Kendra Rumbaugh2, Joseph Wolcott3, Nicole Phillips4, Caleb Phillips1
1Biological Sciences, Texas Tech University, Lubbock, TX, United States 2Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, United States 3Southwest Regional Wound Care Center, Lubbock, TX, United States 4Microbiology, Immunology & Genetics, University of North Texas Health Science Center, Fort Worth, TX, United States
P1.03. Does Opat Improve Long Term Outcomes Following Hospitilization For Foot Infections?
Arthur Tarricone1, Mario Reyes1, Mehmet Suludere1, Lee Rogers2, Lawrence A. Lavery1
1Plastic Surgery , University of Texas Southwestern, Dallas, TX, United States 2Department of Orthopedics, University of Texas Health Science Center, San Antonio, TX, United States
Arthur Tarricone1, Mario Reyes1, Mehmet Suludere1, Lee Rogers2, Lawrence A. Lavery1
1Plastic Surgery , University of Texas Southwestern, Dallas, TX, United States 2Department of Orthopedics, University of Texas Health Science Center, San Antonio, TX, United States
P1.04. Impact Of Diagnostic Delay On Healing Outcomes And Healthcare Utilization In Patients With Pyoderma Gangrenosum
Olivia M. Haddadin1, Katherine M. Erickson2, Emile Latour1, Jonathan Sisley1, Alex Ortega-Loayza1
1OHSU, Portland, OR, United States 2NYMC, New York, NY, United States
Olivia M. Haddadin1, Katherine M. Erickson2, Emile Latour1, Jonathan Sisley1, Alex Ortega-Loayza1
1OHSU, Portland, OR, United States 2NYMC, New York, NY, United States
P1.05. LCM-Directed Profiling Of Acute And Chronic Wounds Identifies Proteomic And Lipidomic Signatures Of Healing And Non-Healing Wounds
Veronika Jurczuk1, Lilian Valadar Tose2, Leticia L. Rodriguez3, Beatriz Abdo Abujamra1, Maria Boulina3, Sinan K. Jabori4, Devinder Singh4, Sara Danker4, Francisco Fernandez Lima2, Ivan Jozic1
1Dermatology, University of Miami School of Medicine, Miami, FL, United States 2Chemistry and Biochemistry, Florida International University, Miami, FL, United States 3Diabetes Research Institute, University of Miami, Miami, FL, United States 4Division of Plastic and Reconstructive Surgery, University of Miami, Miami, FL, United States
Veronika Jurczuk1, Lilian Valadar Tose2, Leticia L. Rodriguez3, Beatriz Abdo Abujamra1, Maria Boulina3, Sinan K. Jabori4, Devinder Singh4, Sara Danker4, Francisco Fernandez Lima2, Ivan Jozic1
1Dermatology, University of Miami School of Medicine, Miami, FL, United States 2Chemistry and Biochemistry, Florida International University, Miami, FL, United States 3Diabetes Research Institute, University of Miami, Miami, FL, United States 4Division of Plastic and Reconstructive Surgery, University of Miami, Miami, FL, United States
P1.06. Staphylococcus Epidermidis Fitness In The Chronic Wound Microenvironment Is Driven By Antimicrobial Resistance Traits
Jamie L. Burgess2, Miroslav Dinic1, Rebecca Verpile2, Tammy Gonzalez2, Jingjing Ming2, Jelena Marjanovic2, Carmen Beliz2, Lisa Plano3, Seth Thaller4, Hadar Lev-Tov2, Marjana Tomic-Canic2, Irena Pastar2
1Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia. 2Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL, United States 3Department of Microbiology and Immunology, University of Miami, Miami, FL, United States 4Department of Surgery, University of Miami, Miami, FL, United States
Jamie L. Burgess2, Miroslav Dinic1, Rebecca Verpile2, Tammy Gonzalez2, Jingjing Ming2, Jelena Marjanovic2, Carmen Beliz2, Lisa Plano3, Seth Thaller4, Hadar Lev-Tov2, Marjana Tomic-Canic2, Irena Pastar2
1Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia. 2Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL, United States 3Department of Microbiology and Immunology, University of Miami, Miami, FL, United States 4Department of Surgery, University of Miami, Miami, FL, United States
P2: Fibrosis/Scarring 2
Moderators: Dorothy Supp & Juan Cortes Troncoso
Moderators: Dorothy Supp & Juan Cortes Troncoso
P2.01. Characterizing Vascular Leakage After Angiopoietin-1 Sirna Knockdown In Dermal Microvascular Endothelial Cells Derived From Post-Burn Hypertrophic Scar
Esteban Molina1, Lauren Moffatt2, Jeffrey W. Shupp3, Bonnie Carney2
1Georgetown University School of Medicine, Clifton, VA, United States 2Firefighters’ Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States 3The Burn Center, Department of Surgery, MedStar Washington Hospital Center, Washington, DC, United States
Esteban Molina1, Lauren Moffatt2, Jeffrey W. Shupp3, Bonnie Carney2
1Georgetown University School of Medicine, Clifton, VA, United States 2Firefighters’ Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States 3The Burn Center, Department of Surgery, MedStar Washington Hospital Center, Washington, DC, United States
P2.02. Endothelial Cell-Derived Extracellular Vesicles And Their Micrornas Downregulate Fibrotic Pathways In Fibroblasts
Heidi Yuan, Anna Salapatas, Trevor R. Leonardo, Chen Han, Devina Koshal, Mateusz S. Wietecha, Lin Chen, Sriram Ravindran, Luisa A. DiPietro
University of Illinois Chicago, Chicago, IL, United States
Heidi Yuan, Anna Salapatas, Trevor R. Leonardo, Chen Han, Devina Koshal, Mateusz S. Wietecha, Lin Chen, Sriram Ravindran, Luisa A. DiPietro
University of Illinois Chicago, Chicago, IL, United States
P2.03 . Radiation Triggers An Early Scarring Response Involving Epithelial-Mesenchymal Transition And Upregulation Of Pro-Fibrotic Genes In A Human Ex Vivo Skin Model
Sophie M. Bilik2, Caroline Dodson2, Gabrielle DiBartolomeo2, Seth Thaller1, Rivka C. Stone2
1Division of Plastic, Aesthetic, and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, FL, United States 2Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States
Sophie M. Bilik2, Caroline Dodson2, Gabrielle DiBartolomeo2, Seth Thaller1, Rivka C. Stone2
1Division of Plastic, Aesthetic, and Reconstructive Surgery, University of Miami Miller School of Medicine, Miami, FL, United States 2Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States
P2.04. Cancer And Lymphatic Marker Foxc2 Drives Wound Healing And Fibrotic Tissue Formation
Maia Granoski1, William Hahn1, Katharina Fischer1, Hudson Kussie1, Dharshan Sivaraj2, Andrew Hostler1, Eamonn McKenna1, Jonathan P. Yasmeh1, Robert Erickson1, Marlys Witte1, Geoffrey C. Gurtner1, Kellen Chen1
1Surgery, University of Arizona, Tucson, AZ, United States 2Stanford University, Palo Alto, CA, United States
Maia Granoski1, William Hahn1, Katharina Fischer1, Hudson Kussie1, Dharshan Sivaraj2, Andrew Hostler1, Eamonn McKenna1, Jonathan P. Yasmeh1, Robert Erickson1, Marlys Witte1, Geoffrey C. Gurtner1, Kellen Chen1
1Surgery, University of Arizona, Tucson, AZ, United States 2Stanford University, Palo Alto, CA, United States
P2.05. Inhibition Of Cyp24a1, An Enzyme Involved In Vitamin D Metabolism, Alters Profibrotic Gene Expression In Keloid-Derived Keratinocytes
Dorothy Supp1, Jennifer Hahn1, Kelly A. Combs1, Heather Powell2
1Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States 2Materials Science Engineering and Biomedical Engineering, The Ohio State University, Columbus, OH, United States
Dorothy Supp1, Jennifer Hahn1, Kelly A. Combs1, Heather Powell2
1Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, United States 2Materials Science Engineering and Biomedical Engineering, The Ohio State University, Columbus, OH, United States
P2.06. Extracorporeal Shock Wave Therapy Alleviate Radiation-Induced Skin Fibrosis By Downregulating Tgf-? Expression
Sangwoo Park
Department of Plastic and Reconstructive Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwonsi, Changwonsi, Korea (the Republic of)
Sangwoo Park
Department of Plastic and Reconstructive Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwonsi, Changwonsi, Korea (the Republic of)
P3: Inflammation
Moderators: Subhadip Ghatak & George Theocharidis
Moderators: Subhadip Ghatak & George Theocharidis
P3.01. Innate Immune Interactions Define Key Mechanisms Of Exosome-Induced Healing Of Chronic Wounds
Kody P. Mansfield, Dianny Almanzar, Bibi S. Subhan, Jasmina Abdalla, Juan Troncoso, Lesly Honore, Piul S. Rabbani
Hansjörg Wyss Department of Plastic Surgery, NYU Langone, Brooklyn, NY, United States
Kody P. Mansfield, Dianny Almanzar, Bibi S. Subhan, Jasmina Abdalla, Juan Troncoso, Lesly Honore, Piul S. Rabbani
Hansjörg Wyss Department of Plastic Surgery, NYU Langone, Brooklyn, NY, United States
P3.02. Topical Fluoxetine Dosage and Administration Chronobiology Affects Cutaneous Wound Healing
Moyasar A. Alhamo1, Anthony Gallegos1, Hsin-ya Yang1, Elham Aslankoohi2, Marcella Gomez3, Marco Rolandi2, Rivkah Isseroff1
1UC Davis Health, Sacramento, CA, United States 2UC, Santa Cruz, CA, United States 3UC, Santa Cruz, CA, United States
Moyasar A. Alhamo1, Anthony Gallegos1, Hsin-ya Yang1, Elham Aslankoohi2, Marcella Gomez3, Marco Rolandi2, Rivkah Isseroff1
1UC Davis Health, Sacramento, CA, United States 2UC, Santa Cruz, CA, United States 3UC, Santa Cruz, CA, United States
P3.03. Skint-1 Regulates Gamma Delta T Cell Activity During Wound Repair
Sujad Younis1, Katelyn Rivas1, Jelena Marjanovic2, Laura Padula1, Jamie L. Burgess2, Ayrimah Malcolm-Parker2, Irena Pastar2, Marjana Tomic-Canic2, Natasa Strbo1
1Microbiology and Immunology, University of Miami, Miami, FL, United States 2University of Miami, Miami, FL, United States
Sujad Younis1, Katelyn Rivas1, Jelena Marjanovic2, Laura Padula1, Jamie L. Burgess2, Ayrimah Malcolm-Parker2, Irena Pastar2, Marjana Tomic-Canic2, Natasa Strbo1
1Microbiology and Immunology, University of Miami, Miami, FL, United States 2University of Miami, Miami, FL, United States
P3.04. Comprehensive Transcriptional Characterization Of Macrophage And Monocyte Dysregulation In Diabetic Wound Healing
Katharina S. Fischer, Abdelrahman Alsharif, Mansi Singh, Filiberto Quintero, Amelia B. Knochel, Maria Gracia Mora Pinos, Fidel Saenz, Ben Litmanovich, Sultana M. Mojadidi, Javier Gonzalez, Dharshan Sivaraj, Hudson C. Kussie, Andrew Hostler, Maia Granoski, Jonathan P Yasmeh, Autumn Lester, Kellen Chen, Geoffrey C Gurtner
Surgery, University of Arizona, Tucson, AZ, United States
Katharina S. Fischer, Abdelrahman Alsharif, Mansi Singh, Filiberto Quintero, Amelia B. Knochel, Maria Gracia Mora Pinos, Fidel Saenz, Ben Litmanovich, Sultana M. Mojadidi, Javier Gonzalez, Dharshan Sivaraj, Hudson C. Kussie, Andrew Hostler, Maia Granoski, Jonathan P Yasmeh, Autumn Lester, Kellen Chen, Geoffrey C Gurtner
Surgery, University of Arizona, Tucson, AZ, United States
P3.05. Excessive Levels Of Neutrophils Cause Macrophage Dysfunction In Fibrotic Volumetric Muscle Loss (Vml) Injury
Ricardo Whitaker, Kara L. Spiller
School of Biomedical Engineering, Sciences and Health Systems, Drexel University, Philadelphia, PA, United States
Ricardo Whitaker, Kara L. Spiller
School of Biomedical Engineering, Sciences and Health Systems, Drexel University, Philadelphia, PA, United States
P3.06. Transcriptomic Predictors Of Oral Mucositis Severity In Head And Neck Cancer Patients
Taichi Goto1, Patricia Corby2, Alexander Lin3, John Lukens3, Stephen Sonis4, Leorey N. Saligan1
1Symptoms Biology Unit, NIH/NINR, Bethesda, MD, United States 2Department of Radiation Oncology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, United States 3Department of Radiation Oncology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, United States 4Brigham and Women's Hospital and the Dana-Farber Cancer Institute, Boston, MA, United States
Taichi Goto1, Patricia Corby2, Alexander Lin3, John Lukens3, Stephen Sonis4, Leorey N. Saligan1
1Symptoms Biology Unit, NIH/NINR, Bethesda, MD, United States 2Department of Radiation Oncology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, United States 3Department of Radiation Oncology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, United States 4Brigham and Women's Hospital and the Dana-Farber Cancer Institute, Boston, MA, United States
P4: Burn and Acute Wounds
Moderators: Lauren Moffatt & Athena Soulika
Moderators: Lauren Moffatt & Athena Soulika
P4.01. 5-Lipoxygenase Exerts Sex-Dependent Effects On Burn Wound Healing
Shannon M. Clayton1, Kristina Sanchez3, Maliha Newsome2, Niayab Ahad2, Athena Soulika1
1Dermatology, UC Davis, Sacramento, CA, United States 2Shriners Hospital for Children Northern California, Sacramento, CA, United States 3Anatomy, Physiology and Cell Biology, UC Davis, Sacramento, CA, United States
Shannon M. Clayton1, Kristina Sanchez3, Maliha Newsome2, Niayab Ahad2, Athena Soulika1
1Dermatology, UC Davis, Sacramento, CA, United States 2Shriners Hospital for Children Northern California, Sacramento, CA, United States 3Anatomy, Physiology and Cell Biology, UC Davis, Sacramento, CA, United States
P4.02. Angiography: A Limb Salvage Strategy Following Lower Extremity Thermal Injury In Patients With Diabetes Mellitus And Peripheral Artery Disease
Desiree Pinto1, Isabel Snee1, Saher Sabri2, Lauren Moffatt1, Taryn Travis1, Jeffrey W. Shupp2, Shawn Tejiram1
1Firefighter's Burn and Surgical Research Laboratory, Washington, DC, United States 2The Burn Center, MedStar Washington Hospital Center, Washington, DC, United States
Desiree Pinto1, Isabel Snee1, Saher Sabri2, Lauren Moffatt1, Taryn Travis1, Jeffrey W. Shupp2, Shawn Tejiram1
1Firefighter's Burn and Surgical Research Laboratory, Washington, DC, United States 2The Burn Center, MedStar Washington Hospital Center, Washington, DC, United States
P4.03. Evaluation Of Subcutaneous Combination Ibuprofen And Resolvin D2 Therapy To Mitigate Burn Progression
Marc Thompson1, Sergio Garcia1, Lucy Shaffer1, Michelle Holik1, David Larson1, Logan Leatherman1, Valeta Sanders1, Anna Ochoa1, LTC Julie Rizzo2, Robert Christy1, Christine Kowalczewski1
1US Army Institute of Surgical Research, JBSA Ft. Sam Houston, TX, United States 2Trauma Surgery, Brooke Army Medical Center, JBSA Ft Sam Houston, TX, United States
Marc Thompson1, Sergio Garcia1, Lucy Shaffer1, Michelle Holik1, David Larson1, Logan Leatherman1, Valeta Sanders1, Anna Ochoa1, LTC Julie Rizzo2, Robert Christy1, Christine Kowalczewski1
1US Army Institute of Surgical Research, JBSA Ft. Sam Houston, TX, United States 2Trauma Surgery, Brooke Army Medical Center, JBSA Ft Sam Houston, TX, United States
P4.04. ELU42, A Small Molecule Wnt Signaling Inhibitor, Significantly Accelerates Wound Closure And Promotes Regenerative Repair Following Cutaneous And Third-Degree Burn Injury In Yorkshire Pigs
Daniel Holsworth, Sarika Saraswati, John Delgado, Michael Stone
Eluciderm Inc, San Diego , CA, United States
Daniel Holsworth, Sarika Saraswati, John Delgado, Michael Stone
Eluciderm Inc, San Diego , CA, United States
P4.05. The Use Of Therapeutics Peptides With Full-Thickness Skin Columns To Improve Healing Of Excisional Wounds
Kristo Nuutila1, Anders Carlson2, Sean Christy2, David Larson2, Chan Rodney2, Thomas Darling3, Ira M. Herman4
1USAISR, San Antonio, TX, United States 2The Metis Foundation, San Antonio, TX, United States 3USUHS, Bethesda, MD, United States 4TUFTS University, Boston, MA, United States
Kristo Nuutila1, Anders Carlson2, Sean Christy2, David Larson2, Chan Rodney2, Thomas Darling3, Ira M. Herman4
1USAISR, San Antonio, TX, United States 2The Metis Foundation, San Antonio, TX, United States 3USUHS, Bethesda, MD, United States 4TUFTS University, Boston, MA, United States
P4.06. Immediate Application Of Topical Anti-Inflammatory Agents On Burn Wounds And Their Effect On Healing
Jamie Neelon1, Irene Yau2, Kristo Nuutila3
1General Surgery, Brooke Army Medical Center, San Antonio, TX, United States 2General Surgery, William Beaumont Army Medical Center, El Paso, TX, United States 3USAISR, San Antonio, TX, United
Jamie Neelon1, Irene Yau2, Kristo Nuutila3
1General Surgery, Brooke Army Medical Center, San Antonio, TX, United States 2General Surgery, William Beaumont Army Medical Center, El Paso, TX, United States 3USAISR, San Antonio, TX, United
11:30 AM
WHS MEETING ADJOURNS
11:30 AM - 2:00 PM
LUNCH WITH EXHIBITORS